Our knowledge of pluripotent stem cell (PSC) biology has advanced to the point where we
now can generate most cells of the human body in the laboratory. PSC-derived …

Health care and medicine were revolutionized in recent years by the development of
biomaterials, such as stents, implants, personalized drug delivery systems, engineered …

Hydrogels are attractive materials for tissue engineering, but efforts to date have shown
limited ability to produce the microstructural features necessary to promote cellular self …

Biohybrid systems have been developed to better understand the design principles and
coordination mechanisms of biological systems. We consider whether two functional …

Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …

Organ-on-chip systems are promising new in vitro research tools in medical,
pharmaceutical, and biological research. Their main benefit, compared to standard cell …

Microfluidic lab-on-a-chip cell culture techniques have been gaining popularity by offering
the possibility of reducing the amount of samples and reagents and greater control over …

To curb the high cost of drug development, there is an urgent need to develop more
predictive tissue models using human cells to determine drug efficacy and safety in advance …

Abstract 3D bioprinting is emerging as a promising technology for fabricating complex tissue
constructs with tailored biological components and mechanical properties. Recent advances …

Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …