The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the
early paradigm of cell replacement and differentiation as a therapeutic mechanism of action …

Mesenchymal stem cells (MSCs) have been isolated from a variety of tissues, such as bone
marrow, skeletal muscle, dental pulp, bone, umbilical cord and adipose tissue. MSCs are …

Mesenchymal stromal cells (MSC) have been reported to improve bacterial clearance in
preclinical models of Acute Respiratory Distress Syndrome (ARDS) and sepsis. The …

In the recent years, it has been demonstrated that the biological activity of mesenchymal
stem cells (MSCs) is mediated through the release of paracrine factors. Many of these …

Osteoarthritis (OA) is the most widespread musculoskeletal disorder in adults. It leads to
cartilage damage associated with subchondral bone changes and synovial inflammation …

Background Wharton's jelly derived stem cells (WJMSCs) are gaining attention as a possible
clinical alternative to bone marrow derived mesenchymal stem cells (BMMSCs) owing to …

Background Multiple sclerosis (MS) is a progressively debilitating neurological condition in
which the immune system abnormally erodes the myelin sheath insulating the nerves …

Mesenchymal or stromal stem cells (MSC) interact with cells of the immune system in
multiple ways. Modulation of the immune system by MSC is believed to be a therapeutic …

Summary 2018 was the year of the first marketing authorization of an allogeneic stem cell
therapy by the European Medicines Agency. The authorization concerns the use of …

Bone marrow–derived mesenchymal stem cells (MSCs) have demonstrated potential for
regenerative medicine strategies. Knowledge of the way these cells respond to their …