The drug pharmacokinetics is affected upon binding with proteins, thus making drug-protein
interactions crucial. This study investigated the interaction between enzalutamide and …

Aflatoxin B1, a mycotoxin produced by large number of Aspergillus species including
Aspergillus flavus and Aspergillus parasiticus, has been described as the most potent …

This research focuses on obtaining the behavior of chemical compounds with respect to
their molecular weight and optimization energy based on the variation in properties in …

Silver nanoparticles (AgNPs) have several applications in nanoscience and nanomedicine
such as antibacterial, antifungal, anti-inflammatory and anti-angiogenic properties. In the …

Methotrexate (MTX) is advised in the treatment of solid tumours, hematologic malignancies
and autoimmune disorders. On reaching the circulation, 60% of MTX is bound to the proteins …

Dutasteride is a pharmacologically important drug employed to treat prostate cancer. Alpha-
2-macroglobulin (α 2 M) is the primary proteinase inhibitor and is abundant in vertebrate …

Abstract Alpha-2-macroglobulin (α2M) is an essential antiproteinase that is widely
distributed in human plasma. The present study was aimed at investigating the binding of a …

Abstract Alpha 2-macroglobulin (α 2 M) is a physiological macromolecule that facilitates the
clearance of many proteinases, cytokines and growth factors in human. Here, we explored …

Quercetin is a widely used bioflavonoid found in onions, grapes, berries and citrus fruits.
Under certain conditions, quercetin acts as a pro-oxidant thereby generating reactive …

Ifosfamide is an active alkylating chemotherapeutic drug chemically related to nitrogen
mustard. The pharmacokinetics of drugs is affected upon binding with protein, making the …