A major stimulus to study cell proliferation, particularly in rodent carcinogenicity assays and
human tumors, has been the belief that the quantification of this fundamental biological …

Two categories of regulatory T cells (Tregs), nTreg and iTreg, play vital roles in orchestrating
the integrity of a host in the course of an immune response. Tregs commonly belong to …

This study was designed to examine the role of the cytokine interleukin-6 (IL-6) in
environmental air pollutant-induced pulmonary inflammation, injury, and repair. IL-6 …

Proliferating cell nuclear antigen (PCNA), an endogenous nuclear protein, has recently
been used to identify replicating cells. PCNA was compared to tritiated thymidine ([3H]-TdR) …

To determine the effects of aged and diluted sidestream cigarette smoke (ADSS) as a
surrogate of environmental tobacco smoke (ETS) on ozone-induced lung injury, male …

Nonylphenol (NP) and 4-Octylphenol (4OP) have shown estrogenic properties both in vivo
and in vitro. Researchers have known for years that estrogens induce a wide number of …

The effects of dietary restriction on the induction of unscheduled DNA synthesis (UDS) and
replicative DNA synthesis (RDS) were studied in the hepatocytes of F344 rats exposed in …

The aim of this study was to evaluate the acute hepatic effects exerted by the steroid
hormone progesterone (PR) in the rat. Although the liver is not a target tissue for this …

Objectives: To investigate the effect of low molecular weight heparin (LMWH) on neointimal
proliferation in cultured human saphenous vein, a model of human vein graft intimal …

Abstract Male Sprague-Dawley rats were exposed to aged and diluted sidestream smoke
(ADSS) from Kentucky 1R4F reference cigarettes for 6 h/day, 5 days/wk, for a 13-wk period …