ImmunoPET: concept, design, and applications
W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …
Click chemistry: a transformative technology in nuclear medicine
Abstract The 2022 Nobel Prize in Chemistry was awarded to Professors K. Barry Sharpless,
Morten Meldal and Carolyn Bertozzi for their pioneering roles in the advent of click …
Morten Meldal and Carolyn Bertozzi for their pioneering roles in the advent of click …
[HTML][HTML] Current update on nanoplatforms as therapeutic and diagnostic tools: A review for the materials used as nanotheranostics and imaging modalities
In the last decade, the use of nanotheranostics as emerging diagnostic and therapeutic tools
for various diseases, especially cancer, is held great attention. Up to date, several …
for various diseases, especially cancer, is held great attention. Up to date, several …
Click chemistry and radiochemistry: an update
The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …
Zirconium immune-complexes for PET molecular imaging: current status and prospects
L Melendez-Alafort, G Ferro-Flores, L De Nardo… - Coordination Chemistry …, 2023 - Elsevier
Diagnostic molecular images, obtained by positron emission tomography (PET), have
successfully functioned as sensitive tools for detecting and monitoring the treatment of …
successfully functioned as sensitive tools for detecting and monitoring the treatment of …
Not so innocent: Impact of fluorophore chemistry on the in vivo properties of bioconjugates
The combination of targeting ligands and fluorescent dyes is a powerful strategy to observe
cell types and tissues of interest. Conjugates of peptides, proteins, and, in particular …
cell types and tissues of interest. Conjugates of peptides, proteins, and, in particular …
Identification of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer by Using HER2-targeted 89Zr-Pertuzumab …
Background Human epidermal growth factor receptor 2 (HER2)-targeted therapies are
successful in patients with HER2-positive malignancies; however, spatial and temporal …
successful in patients with HER2-positive malignancies; however, spatial and temporal …
Development of antibody immuno-PET/SPECT radiopharmaceuticals for imaging of oncological disorders—an update
J Dewulf, K Adhikari, C Vangestel, TVD Wyngaert… - Cancers, 2020 - mdpi.com
Positron emission tomography (PET) and single-photon emission computed tomography
(SPECT) are molecular imaging strategies that typically use radioactively labeled ligands to …
(SPECT) are molecular imaging strategies that typically use radioactively labeled ligands to …
Lysine-directed site-selective bioconjugation for the creation of radioimmunoconjugates
SM Sarrett, C Rodriguez, G Rymarczyk… - Bioconjugate …, 2022 - ACS Publications
The synthesis of radioimmunoconjugates via the stochastic attachment of bifunctional
chelators to lysines can yield heterogeneous products with suboptimal in vitro and in vivo …
chelators to lysines can yield heterogeneous products with suboptimal in vitro and in vivo …
First-in-Human Evaluation of Site-Specifically Labeled 89Zr-Pertuzumab in Patients with HER2-Positive Breast Cancer
R Yeh, JA O'Donoghue… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Radioimmunoconjugates targeting human epidermal growth factor receptor 2 (HER2) have
shown potential to noninvasively visualize HER2-positive tumors. However, the stochastic …
shown potential to noninvasively visualize HER2-positive tumors. However, the stochastic …