Neuroblastoma is the most common extracranial solid tumor in childhood accounting for 8–
10% of all childhood malignancies. The tumor is characterized by a spectrum of …

Peripheral neuroblastic tumors (neuroblastoma, ganglioneuroblastoma and
ganglioneuroma) are heterogeneous and their diverse and wide range of clinical behaviors …

Background: MYCN amplification with subsequent MYCN protein overexpression is a
powerful indicator of poor prognosis of neuroblastoma patients. Little is known regarding the …

BACKGROUND This study sought to investigate biological/clinicopathological
characteristics of neuroblastoma, undifferentiated subtype (NBUD). METHODS This study …

The International Neuroblastoma Pathology Classification (INPC), which distinguishes a
favorable histology (FH) and an unfavorable histology (UH), is one of the most powerful …

Prognostic effects of Mitosis-Karyorrhexis Index (MKI) used in the International
Neuroblastoma Pathology Classification (INPC) are age-dependent. A total of 4,282 …

Neuroblastomas with a high mitosis-karyorrhexis index (High-MKI) are often associated with
MYCN amplification, MYCN protein overexpression and adverse clinical outcome. However …

Aims To investigate the relations between anaplastic lymphoma kinase (ALK) and v-myc
myelocytomatosis viral related oncogene neuroblastoma derived homolog (MYCN) protein …

Abstract Stage 4S neuroblastoma (4SNB) is associated with spontaneous tumor regression
and an excellent prognosis. However, a small group of the patients have a poor prognosis …

Background Ganglioneuroblastoma intermixed (GNBI) is classified as “favorable” histology
by International Neuroblastoma Pathology Classification system. However, the International …