The COVID-19 pandemic is an extraordinary global emergency that has led to the
implementation of unprecedented measures in order to stem the spread of the infection …

Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Sarcopenia is one of the main issues associated with the process of aging. Characterized by
muscle mass loss, it is triggered by several conditions, including sedentary habits and …

Various diseases can cause skeletal muscle atrophy, usually accompanied by inflammation,
mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced …

Muscle RING finger 1 (MuRF1) and muscle atrophy F-box (MAFbx)/atrogin-1 were identified
more than 10 years ago as two muscle-specific E3 ubiquitin ligases that are increased …

Muscle atrophy is caused by an imbalance in contractile protein synthesis and degradation
which can be triggered by various conditions including Type 2 Diabetes Mellitus (T2DM) …

Loss of skeletal muscle mass occurs frequently in clinical settings in response to joint
immobilization and bed rest, and is induced by a combination of unloading and inactivity …

Spinal cord injury (SCI) is a devastating event that results in significant physical disabilities
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …

Skeletal muscle fibers are malleable and undergo rapid remodeling in response to
increased contractile activity (ie, exercise) or prolonged periods of muscle inactivity (eg …

Rotator cuff tears are the most common upper extremity condition seen by primary care and
orthopaedic surgeons, with a spectrum ranging from tendinopathy to full-thickness tears with …