Deciphering the role of RNA-binding proteins in the post-transcriptional control of gene expression

S Kishore, S Luber, M Zavolan - Briefings in functional genomics, 2010 - academic.oup.com
Eukaryotic cells express a large variety of ribonucleic acid-(RNA)-binding proteins (RBPs)
with diverse affinity and specificity towards target RNAs that play a crucial role in almost …

Musashi signaling in stem cells and cancer

RG Fox, FD Park, CS Koechlein… - Annual review of cell …, 2015 - annualreviews.org
How a single cell gives rise to an entire organism is one of biology's greatest mysteries.
Within this process, stem cells play a key role by serving as seed cells capable of both self …

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

MG Kharas, CJ Lengner, F Al-Shahrour, L Bullinger… - Nature medicine, 2010 - nature.com
RNA-binding proteins of the Musashi (Msi) family are expressed in stem cell compartments
and in aggressive tumors, but they have not yet been widely explored in the blood. Here we …

Stress granules involved in formation, progression and metastasis of cancer: A scoping review

MR Asadi, D Rahmanpour, MS Moslehian… - Frontiers in cell and …, 2021 - frontiersin.org
The assembly of stress granules (SGs) is a well-known cellular strategy for reducing stress-
related damage and promoting cell survival. SGs have become important players in human …

Heterogeneous nuclear ribonucleoprotein K is associated with poor prognosis and regulates proliferation and apoptosis in bladder cancer

X Chen, P Gu, R Xie, J Han, H Liu… - Journal of cellular …, 2017 - Wiley Online Library
Heterogeneous nuclear ribonucleoprotein K (hn RNPK) is an essential RNA‐and DNA‐
binding protein that regulates diverse biological events, especially DNA transcription. hn …

The novel KLF4/MSI2 signaling pathway regulates growth and metastasis of pancreatic cancer

K Guo, J Cui, M Quan, D Xie, Z Jia, D Wei, L Wang… - Clinical Cancer …, 2017 - AACR
Abstract Purpose: Musashi 2 (MSI2) is reported to be a potential oncoprotein in cases of
leukemia and several solid tumors. However, its expression, function, and regulation in …

Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial–mesenchymal transition

L He, X Zhou, C Qu, L Hu, Y Tang… - Journal of cellular …, 2014 - Wiley Online Library
The high incidence of recurrence and the poor prognosis of hepatocellular carcinoma (HCC)
necessitate the discovery of new predictive markers of HCC invasion and prognosis. In this …

[HTML][HTML] MiR-330-3p inhibits gastric cancer progression through targeting MSI1

A Guan, H Wang, X Li, H Xie, R Wang… - American journal of …, 2016 - ncbi.nlm.nih.gov
Increasing evidences demonstrated that microRNAs (miRNAs) play critical roles in the
human tumor development and progression. In our study, we found that miR-330-3p …

[HTML][HTML] The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis

DT Vo, D Subramaniam, M Remke, TL Burton… - The American journal of …, 2012 - Elsevier
Musashi1 (Msi1) is a highly conserved RNA-binding protein that is required during the
development of the nervous system. Msi1 has been characterized as a stem cell marker …

WNT and NOTCH signaling pathways as activators for epidermal growth factor receptor in esophageal squamous cell carcinoma

MR Abbaszadegan, A Riahi, MM Forghanifard… - Cellular & molecular …, 2018 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is the most common histological
type of esophageal cancer, with a poor prognosis. Deregulation of WNT and NOTCH …