miRNAs as potential game-changers in renal cell carcinoma: Future clinical and medicinal uses

MS Elballal, AAM Sallam, AE Elesawy… - … -Research and Practice, 2023 - Elsevier
Renal cell carcinoma (RCC) has the highest mortality rate of all genitourinary cancers, and
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …

The role of non-coding RNAs in ABC transporters regulation and their clinical implications of multidrug resistance in cancer

Y Wang, Y Wang, Z Qin, S Cai, L Yu… - Expert opinion on drug …, 2021 - Taylor & Francis
Introduction Multi-drug resistance (MDR) is a hindrance toward the successful treatment of
cancers. The primary mechanism that gives rise to acquired chemoresistance is the …

[HTML][HTML] SUV39H1 deficiency suppresses clear cell renal cell carcinoma growth by inducing ferroptosis

J Wang, X Yin, W He, W Xue, J Zhang… - Acta Pharmaceutica Sinica …, 2021 - Elsevier
Clear cell renal cell carcinoma (ccRCC) is a common kidney malignancy characterized by a
poor prognosis. Suppressor of variegation 3–9 homolog 1 (SUV39H1), which encodes a …

Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC

W Xue, W Jian, Y Meng, T Wang, L Cai, Y Yu… - Cell Death & …, 2023 - nature.com
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer and is
associated with poor prognosis. The histone H3 lysine 36 methyltransferase SET-domain …

MicroRNA-302a-3p induces ferroptosis of non-small cell lung cancer cells via targeting ferroportin

D Wei, YQ Ke, P Duan, L Zhou, CY Wang… - Free radical …, 2021 - Taylor & Francis
Ferroptosis is a newly described regulated form of cell death that contributes to the
progression of non-small cell lung cancers (NSCLCs). MicroRNA-302a-3p (miR-302a-3p) …

LncRNA regulation: New frontiers in epigenetic solutions to drug chemoresistance

Y Zhou, W Sun, Z Qin, S Guo, Y Kang, S Zeng… - Biochemical …, 2021 - Elsevier
Long-noncoding RNAs (lncRNAs) have been shown to participate in sensitizing or de-
sensitizing cancer cells to chemical drugs during cancer therapeutics. Notably, a plethora of …

MicroRNA signature in renal cell carcinoma

S Ghafouri-Fard, Z Shirvani-Farsani, W Branicki… - Frontiers in …, 2020 - frontiersin.org
Renal cell carcinoma (RCC) includes 2.2% of all diagnosed cancers and 1.8% of cancer-
related mortalities. The available biomarkers or screening methods for RCC suffer from lack …

Potential of miR-181a-5p and miR-630 as clinical biomarkers in NSCLC

J Simiene, D Dabkeviciene, D Stanciute… - BMC cancer, 2023 - Springer
Background The development of drug resistance and high mortality rates are the major
problems observed in non-small cell lung cancer (NSCLC). Biomarkers indicating and …

LEF1-AS1 accelerates tumorigenesis in glioma by sponging miR-489-3p to enhance HIGD1A

Z Cheng, G Wang, W Zhu, C Luo, Z Guo - Cell death & disease, 2020 - nature.com
Long non-coding (lncRNA) lymphoid enhancer-binding factor 1 antisense RNA 1 (LEF1-
AS1) has been validated to be implicated in manifold cancers, whereas its function in glioma …

Regulation of solute carriers oct2 and OAT1/3 in the kidney: a phylogenetic, ontogenetic, and cell dynamic perspective

C Pou Casellas, K Jansen… - Physiological …, 2022 - journals.physiology.org
Over the course of more than 500 million years, the kidneys have undergone a remarkable
evolution from primitive nephric tubes to intricate filtration-reabsorption systems that …