Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

Hydrogen sulfide (H 2 S) was initially recognized as a toxic gas and its biological functions
in mammalian cells have been gradually discovered during the past decades. In the latest …

M1 macrophages enter a glycolytic state when endogenous nitric oxide (NO) reprograms
mitochondrial metabolism by limiting aconitase 2 and pyruvate dehydrogenase (PDH) …

Nitroxyl (HNO) is the one-electron reduced and protonated congener of nitric oxide (• NO),
owning a distinct chemical profile. Based on real-time detection, we demonstrate that HNO is …

Nitroxyl (HNO) and endoplasmic reticulum (ER) stress are considered to play important
effects in the administration of many pathological processes of Parkinson's disease (PD) …

Azanone (HNO) is a reactive nitrogen species with pronounced biological activity and high
therapeutic potential for cardiovascular dysfunction. A critical barrier to understanding the …

Interactions between small inorganic molecules are fundamental to the understanding of
basic reaction mechanisms and some of the initial processes of chemical evolution that …

The redox chemistry of H2S with NO and other oxidants containing the NO group is
discussed on a mechanistic basis because of the expanding interest in their biological …

HNO (nitroxyl, azanone), joined the 'biologically relevant reactive nitrogen species' family in
the 2000s. Azanone is impossible to store due to its high reactivity and inherent low stability …

Parkinson's disease (PD) is a neurodegenerative disease common in middle-aged and
older individuals. At present, the exact cause is unknown, and the diagnosis is cumbersome …