Gadolinium deposition in brain: current scientific evidence and future perspectives

BJ Guo, ZL Yang, LJ Zhang - Frontiers in molecular neuroscience, 2018 - frontiersin.org
In the past 4 years, many publications described a concentration-dependent deposition of
gadolinium in the brain both in adults and children, seen as high signal intensities in the …

[HTML][HTML] Intravoxel incoherent motion MRI in neurological and cerebrovascular diseases

AM Paschoal, RF Leoni, AC Dos Santos, FF Paiva - NeuroImage: Clinical, 2018 - Elsevier
Abstract Intravoxel Incoherent Motion (IVIM) is a recently rediscovered noninvasive magnetic
resonance imaging (MRI) method based on diffusion-weighted imaging. It enables the …

Updated clinical practice guideline on use of gadolinium-based contrast agents in kidney disease issued by the Canadian Association of Radiologists

N Schieda, PJ Maralani, C Hurrell… - Canadian …, 2019 - journals.sagepub.com
In 2017, the Canadian Association of Radiologists issued a clinical practice guideline (CPG)
regarding the use of gadolinium-based contrast agents (GBCAs) in patients with acute …

Increased retention of gadolinium in the inflamed brain after repeated administration of gadopentetate dimeglumine: a proof-of-concept study in mice combining ICP …

S Wang, B Hesse, M Roman, D Stier… - Investigative …, 2019 - journals.lww.com
Objectives The aim of this study was to determine in vivo if brain inflammation leads to
increased gadolinium (Gd) retention in brain tissue after repeated applications of Gd-based …

Standardized assessment of the signal intensity increase on unenhanced T1-weighted images in the brain: the European Gadolinium Retention Evaluation …

CC Quattrocchi, J Ramalho, AJ van der Molen… - European …, 2019 - Springer
After the initial report in 2014 on T1-weighted (T1w) hyperintensity of deep brain nuclei
following serial injections of linear gadolinium-based contrast agents (GBCAs), a multitude …

Effect of at least 10 serial gadobutrol administrations on brain signal intensity ratios on T1-weighted MRI in children: a matched case-control study

K Ozturk, D Nascene - American Journal of Roentgenology, 2021 - Am Roentgen Ray Soc
BACKGROUND. An association is recognized between linear gadolinium-based contrast
agents (GBCAs) and intracranial gadolinium retention in children. The relation between …

A retrospective cohort evaluation of the effect of multiple administrations of gadopentetate dimeglumine on brain magnetic resonance imaging T1-weighted signal

AJ Towbin, B Zhang, JR Dillman - Pediatric Radiology, 2021 - Springer
Background Gadolinium deposition occurs following repeated administration of gadolinium-
based contrast media. However, few studies have evaluated factors that lead to increased …

Update on Gadolinium-Based Contrast Agent–Enhanced Imaging in the Genitourinary System

N Schieda, S Krishna… - American Journal of …, 2019 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this article is to review gadolinium-based contrast agent
(GBCA)–enhanced MRI applications in the genitourinary system. CONCLUSION …

Evaluation of the effect of multiple administrations of gadopentetate dimeglumine or gadoterate meglumine on brain T1-weighted hyperintensity in pediatric patients

AJ Towbin, B Zhang, JR Dillman - Pediatric Radiology, 2021 - Springer
Background Repeated administrations of linear gadolinium-based contrast media (GBCM)
are associated with T1-weighted (T1-W) signal intensity change in brain structures …

Gadolinium and Bio-Metal Association: A Concentration Dependency Tested in a Renal Allograft and Investigated by Micro-Synchrotron XRF

W Osterode, G Falkenberg, H Regele - Journal of Imaging, 2022 - mdpi.com
Aims: This study aimed to investigate gadolinium (Gd) and bio-metals in a renal allograft of a
patient who was shortly after transplantation repeatedly exposed to a Gd-based contrast …