Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …

The Role of Macrophages in Staphylococcus aureus Infection

GR Pidwill, JF Gibson, J Cole, SA Renshaw… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

From bacterial killing to immune modulation: Recent insights into the functions of lysozyme

SA Ragland, AK Criss - PLoS pathogens, 2017 - journals.plos.org
Lysozyme is a cornerstone of innate immunity. The canonical mechanism for bacterial killing
by lysozyme occurs through the hydrolysis of cell wall peptidoglycan (PG). Conventional …

Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health

T Li, Z Wang, J Guo, C de la Fuente-Nunez… - Science of The Total …, 2023 - Elsevier
The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

Antimicrobial peptides: features, action, and their resistance mechanisms in bacteria

H Moravej, Z Moravej, M Yazdanparast… - Microbial Drug …, 2018 - liebertpub.com
In recent years, because of increased resistance to conventional antimicrobials, many
researchers have started to study the synthesis of new antibiotics to control the disease …

[HTML][HTML] Mechanisms and consequences of bacterial resistance to antimicrobial peptides

DI Andersson, D Hughes… - Drug Resistance Updates, 2016 - Elsevier
Cationic antimicrobial peptides (AMPs) are an intrinsic part of the human innate immune
system. Over 100 different human AMPs are known to exhibit broad-spectrum antibacterial …

Membrane targeting cationic antimicrobial peptides

D Ciumac, H Gong, X Hu, JR Lu - Journal of colloid and interface science, 2019 - Elsevier
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …

Bacterial membrane lipids: diversity in structures and pathways

C Sohlenkamp, O Geiger - FEMS microbiology reviews, 2016 - academic.oup.com
For many decades, Escherichia coli was the main model organism for the study of bacterial
membrane lipids. The results obtained served as a blueprint for membrane lipid …

[HTML][HTML] Molecular mechanisms of membrane targeting antibiotics

RM Epand, C Walker, RF Epand… - Biochimica et Biophysica …, 2016 - Elsevier
The bacterial membrane provides a target for antimicrobial peptides. There are two groups
of bacteria that have characteristically different surface membranes. One is the Gram …