High on-clopidogrel platelet reactivity in ischaemic stroke or transient ischaemic attack: systematic review and meta-analysis

V Alakbarzade, X Huang, IC Ster, M McEntagart… - Journal of Stroke and …, 2020 - Elsevier
Objectives To assess the prevalence of high on-clopidogrel platelet reactivity (HCPR) in
patients with ischaemic stroke or transient ischaemic attack (IS/TIA), their outcome and …

[HTML][HTML] Discontinuation of Plavix®(clopidogrel) for hip fracture surgery. A systematic review of the literature

L Mattesi, T Noailles, N Rosencher… - … & Traumatology: Surgery …, 2016 - Elsevier
The elderly population is increasing worldwide, associated with an increase in diseases
related to aging, such as hip fractures. These patients are sometimes treated with …

Effects of 12-week supplementation of marine Omega-3 PUFA-based formulation Omega3Q10 in older adults with prehypertension and/or elevated blood cholesterol

T Shen, G Xing, J Zhu, S Zhang, Y Cai, D Li… - Lipids in health and …, 2017 - Springer
Backgrounds To study the effects of supplementation of a marine omega-3 poly-unsaturated
fatty acids (n3-PUFA) formulation (Omega3Q10) in older adults with hypertension and/or …

Both CYP2C19 and PON1 Q192R genotypes influence platelet response to clopidogrel by thrombelastography in patients with acute coronary syndrome

W Peng, X Shi, X Xu, Y Lin - Cardiovascular Therapeutics, 2019 - Wiley Online Library
Objective. The objective of this study is to explore the relationships of the effects of
CYP2C19 and PON1 Q192R polymorphism on the activity of clopidogrel and the risk of high …

Aspirin and clopidogrel resistance in Indian patients with ischemic stroke and its associations with gene polymorphisms: A pilot study

S Patel, V Arya, A Saraf, M Bhargava… - Annals of Indian …, 2019 - journals.lww.com
Methods: Platelet function testing by light transmission aggregometry was performed on 65
patients with ischemic stroke who were stable on dual antiplatelet therapy (clopidogrel 75 …

Clopidogrel‐associated genetic variants on inhibition of platelet activity and clinical outcome for acute coronary syndrome patients

X Li, Z Wang, Q Wang, Q Xu… - Basic & Clinical …, 2019 - Wiley Online Library
Acute coronary syndrome (ACS) has become a vital disease with high mortality worldwide. A
combined antiplatelet therapy (aspirin and a P2Y12 antagonist) is commonly used to …

[PDF][PDF] Do we really need genetic tests in current clinical practice?

C Bănescu - Revista Romana de Medicina de Laborator, 2019 - sciendo.com
Currently there is an increased number of genetic tests available for disorders produced by
chromosomal or gene abnormalities. Some genetic tests are recommended by healthcare …

Clopidogrel responder status is uninfluenced by CYP2C19* 2 in Danish patients with stroke

CL Rath, NR Jørgensen, T Wienecke - Plos one, 2020 - journals.plos.org
Background Antiplatelet therapy is a cornerstone of secondary stroke prevention, but the
responsiveness to antiplatelet medication varies among patients. Clopidogrel is a pro-drug …

Assessment of risk factors for drug resistance of dual anti platelet therapy after PCI

L Zhang, Y Lv, J Dong, N Wang… - Clinical and Applied …, 2022 - journals.sagepub.com
Since aspirin and clopidogrel are the widely and conventionally used drugs to treat acute
myocardial infarction after percutaneous coronary intervention (PCI), it is important to …

A Pharmacogenetic Study of CYP2C19 in Acute Coronary Syndrome Patients of Colombian Origin Reveals New Polymorphisms Potentially Related to Clopidogrel …

M Angulo-Aguado, K Panche… - Journal of Personalized …, 2021 - mdpi.com
Clopidogrel, an oral platelet P2Y12 receptor blocker, is used in the treatment of acute
coronary syndrome. Interindividual variability in treatment response and the occurrence of …