The X-linked muscle-wasting disease Duchenne muscular dystrophy is caused by mutations
in the gene encoding dystrophin. There is currently no effective treatment for the disease; …

Brain function is inextricably coupled to water homeostasis. The fact that most of the volume
between neurons is occupied by glial cells, leaving only a narrow extracellular space …

Chronic pain is highly prevalent worldwide and represents a significant socioeconomic and
public health burden. Several aspects of chronic pain, for example back pain and a severity …

We present and discuss the role of endothelial and astroglial cells in managing the blood-
brain barrier (BBB) and aspects of pathological alterations in the BBB. The impact of …

Duchenne muscular dystrophy (DMD) is caused by frameshift mutations in the DMD gene
that prevent the body-wide translation of its protein product, dystrophin. Besides a severe …

Prior evidence has supported the existence of multiple susceptibility genes for
schizophrenia. Multipoint linkage analysis of the 270 Irish high-density pedigrees that we …

The Aquaporin-4 (AQP4) water channel contributes to brain water homeostasis in
perivascular astrocyte endfeet where it is concentrated. We postulated that AQP4 is tethered …

Laminins are major constituents of the gliovascular basal lamina of the blood–brain barrier
(BBB); however, the role of laminins in BBB development remains unclear. Here we report …

Mutations of different components of the dystrophin–glycoprotein complex (DGC) cause
muscular dystrophies that vary in terms of severity, age of onset, and selective involvement …

Eleven studies now report significant associations between schizophrenia and certain
haplotypes of single-nucleotide polymorphisms in the gene encoding dysbindin-1 at 6p22 …