Bone morphogenetic protein signaling in cancer; some topics in the recent 10 years

S Ehata, K Miyazono - Frontiers in cell and developmental biology, 2022 - frontiersin.org
Bone morphogenetic proteins (BMPs), members of the transforming growth factor-β (TGF-β)
family, are multifunctional cytokines. BMPs have a broad range of functions, and …

Potential of the miR-200 family as a target for developing anti-cancer therapeutics

H Jo, K Shim, D Jeoung - International Journal of Molecular Sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs (18–24 nucleotides) that play significant
roles in cell proliferation, development, invasion, cancer development, cancer progression …

Identification of anoikis-related subgroups and prognosis model in liver hepatocellular carcinoma

Y Chen, W Huang, J Ouyang, J Wang, Z Xie - International journal of …, 2023 - mdpi.com
Resistance to anoikis is a key characteristic of many cancer cells, promoting cell survival.
However, the mechanism of anoikis in hepatocellular carcinoma (HCC) remains unknown …

Aberrant expression of bone morphogenetic proteins in the disease progression and metastasis of breast cancer

M Liu, L Sui, Z Fang, WG Jiang, L Ye - Frontiers in Oncology, 2023 - frontiersin.org
Background Bone morphogenetic proteins (BMPs) play crucial roles in the tumorigenesis
and metastasis of cancers. Controversy remains about the exact implications of BMPs and …

An anoikis-based signature for predicting prognosis in hepatocellular carcinoma with machine learning

Z Guizhen, Z Weiwei, W Yun, C Guangying… - Frontiers in …, 2023 - frontiersin.org
Background: Hepatocellular carcinoma (HCC) is a common malignancy with high mortality
worldwide. Despite advancements in diagnosis and treatment in recent years, there is still …

Self-Renewal Inhibition in Breast Cancer Stem Cells: Moonlight Role of PEDF in Breast Cancer

C Gil-Gas, M Sánchez-Díez, P Honrubia-Gómez… - Cancers, 2023 - mdpi.com
Simple Summary While more efficient cancer treatments have led to a better quality of life
and to five-year survival rates of over 85% for localized tumors, these rates remain below …

Predicting the immune microenvironment and prognosis with a anoikis-related signature in breast cancer

X Lu, Q Yuan, C Zhang, S Wang, W Wei - Frontiers in Oncology, 2023 - frontiersin.org
Background Tumor heterogeneity is widely recognized as a crucial factor impacting the
prognosis of breast cancer (BC) patients. However, there remains an insufficient …

[HTML][HTML] BMP signaling inhibition overcomes chemoresistance of prostate cancer

C Xie, Z Wang, Y Ba, J Aguilar, A Kyan… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Chemoresistance is a major therapeutic challenge to prostate cancer and its underlying
molecular mechanism is poorly understood. Previously, it has been suggested that bone …

Anoikis in cell fate, physiopathology, and therapeutic interventions

J Mei, XY Jiang, HX Tian, DC Rong, JN Song… - MedComm, 2024 - Wiley Online Library
The extracellular matrix (ECM) governs a wide spectrum of cellular fate processes, with a
particular emphasis on anoikis, an integrin‐dependent form of cell death. Currently, anoikis …

Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes

HM Sonnemann, B Pazdrak, B Nassif… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction Vestigial-like 1 (VGLL1) is a co-transcriptional activator that binds to TEA
domain-containing transcription factors (TEADs). Its expression is upregulated in a variety of …