Acute-on-chronic liver failure clinical guidelines

JS Bajaj, JG O'Leary, JC Lai, F Wong… - Official journal of the …, 2022 - journals.lww.com
In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging
as a major cause of mortality. These guidelines indicate the preferred approach to the …

Hepatic encephalopathy: a critical current review

A Hadjihambi, N Arias, M Sheikh, R Jalan - Hepatology international, 2018 - Springer
Hepatic encephalopathy (HE) is a serious neuropsychiatric complication of cirrhosis and/or
porto-systemic shunting. The clinical symptoms are widely variable, extending from subtle …

[HTML][HTML] Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013

R Jalan, J Fernandez, R Wiest, B Schnabl… - Journal of …, 2014 - Elsevier
Bacterial infections are very common and represent one of the most important reasons of
progression of liver failure, development of liver-related complications, and mortality in …

[HTML][HTML] Hepatic encephalopathy in patients with acute decompensation of cirrhosis and acute-on-chronic liver failure

M Romero-Gómez, S Montagnese, R Jalan - Journal of Hepatology, 2015 - Elsevier
Hepatic encephalopathy in a hospitalized cirrhotic patient is associated with a high mortality
rate and its presence adds further to the mortality of patients with acute-on-chronic liver …

Infections complicating cirrhosis

S Piano, A Brocca, S Mareso, P Angeli - Liver International, 2018 - Wiley Online Library
Patients with cirrhosis have a high risk of bacterial infections. Bacterial infections induce
systemic inflammation that may lead to organ failure and acute‐on‐chronic liver failure …

Hepatic encephalopathy

P Ferenci - Gastroenterology report, 2017 - academic.oup.com
Hepatic encephalopathy (HE) is a reversible syndrome of impaired brain function occurring
in patients with advanced liver diseases. The precise pathophysiology of HE is still under …

[HTML][HTML] Changes in the epidemiology and management of bacterial infections in cirrhosis

S Piano, M Tonon, P Angeli - Clinical and Molecular Hepatology, 2021 - ncbi.nlm.nih.gov
Patients with cirrhosis are susceptible to develop infections because of immune dysfunction,
changes in microbiome and increase in bacterial translocation from the gut to systemic …

[PDF][PDF] Proton pump inhibitors are associated with minimal and overt hepatic encephalopathy and increased mortality in patients with cirrhosis

S Nardelli, S Gioia, L Ridola, A Farcomeni, M Merli… - …, 2019 - Wiley Online Library
Minimal hepatic encephalopathy (MHE) is a subclinical cognitive impairment frequently
observable in patients with cirrhosis. Proton pump inhibitors (PPIs) can contribute to small …

Old and new precipitants in hepatic encephalopathy: A new look at a field in continuous evolution

D Bellafante, S Gioia, J Faccioli, O Riggio… - Journal of Clinical …, 2023 - mdpi.com
Hepatic encephalopathy (HE) is a common complication in patients with advanced liver
disease. It is a brain dysfunction characterized by neurological and psychiatric symptoms …

The shaping of gut immunity in cirrhosis

L Muñoz, E Caparrós, A Albillos, R Francés - Frontiers in Immunology, 2023 - frontiersin.org
Cirrhosis is the common end-stage of chronic liver diseases of different etiology. The altered
bile acids metabolism in the cirrhotic liver and the increase in the blood-brain barrier …