Anticancer metallodrugs based on ruthenium and osmium are among the most investigated
and advanced non-platinum metallodrugs. Inorganic drug discovery with these agents has …

The quest for alternative drugs to the well-known cisplatin and its derivatives, which are still
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …

DNA has a strong affinity for many heterocyclic aromatic dyes, such as acridine and its
derivatives. Lerman in 1961 first proposed intercalation as the source of this affinity, and this …

Neutral or cationic arene ruthenium complexes providing both hydrophilic as well as
hydrophobic properties due to the robustness of the ruthenium–arene unit hold a high …

Ruthenium complexes exhibit a broad variety of biological and biomedical activities
including anticancer efficiency. The reason is that the octahedral bonding of both Ru (II) and …

Nanotechnology is an evolving field with enormous potential for biomedical applications.
The growing interest to use inorganic nanoparticles in medicine is due to the unique size …

Ruthenium (II) polypyridine complexes are one of the most extensively studied and
developed systems in the family of luminescent transition-metal complexes. Notably, there …

The combination of reaction-oriented electrochemistry with species-focussed spectroscopy
in spectroelectrochemistry (SEC) allows for a more complete analysis of single and multiple …

The fields of phototherapy and of inorganic chemotherapy both have long histories.
Inorganic photoactivated chemotherapy (PACT) offers both temporal and spatial control over …

The introduction of multifunctionalities for tumour targeting is becoming a popular strategy
toward the development of new therapeutic agents. In particular, the multifaceted potential of …