Bioprospecting is the exploration, extraction and screening of biological material and
sometimes indigenous knowledge to discover and develop new drugs and other products …

Abstract Development of new anti-bacterial agents acting upon underexploited targets and
thus evading known mechanisms of resistance is the need of the hour. The highly conserved …

Antimicrobial peptides (AMPs) are promising therapeutic agents for treating antibiotic-
resistant bacterial infections. Previous studies showed that magainin 2 (isolated from African …

In parallel to the uncontrolled use of antibiotics, the emergence of multidrug-resistant
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …

A significant opportunistic pathogen, Acinetobacter baumannii (A. baumannii) has evolved
mechanisms of resistance to a wide variety of antimicrobials, including carbapenems. In this …

Treatments for 'superbug'infections are the focus for innovative research, as drug resistance
threatens human health and medical practices globally. In particular, Acinetobacter …

What is known and Objective: The widespread use of antibiotics as therapeutic agents
caused an increase of multidrug resistant bacteria (MDR) appearance. Regarding MDRs …

The threat of diminished antibiotic discovery has global health care in crisis. In the United
States, it is estimated each year that over 2 million bacterial infections are resistant to first …

Enoyl-acyl carrier protein reductase (FabI) is a key enzyme in the fatty acid metabolism of
gram-positive bacteria and is considered a potential target for new antibacterial drugs …

The emergence of multidrug-resistant bacteria and the poor efficacy of available antibiotics
against these infections have led to the urgent need for novel antibiotics. Acinetobacter …