Bioactive compounds from marine sponges: Fundamentals and applications

D Varijakzhan, JY Loh, WS Yap, K Yusoff, R Seboussi… - Marine drugs, 2021 - mdpi.com
Marine sponges are sessile invertebrates that can be found in temperate, polar and tropical
regions. They are known to be major contributors of bioactive compounds, which are …

Ten-year research update review: Antiviral activities from marine organisms

G Riccio, N Ruocco, M Mutalipassi, M Costantini… - Biomolecules, 2020 - mdpi.com
Oceans cover more than 70 percent of the surface of our planet and are characterized by
huge taxonomic and chemical diversity of marine organisms. Several studies have shown …

Antifungal and antiviral products of marine organisms

RCF Cheung, JH Wong, WL Pan, YS Chan… - Applied microbiology …, 2014 - Springer
Marine organisms including bacteria, fungi, algae, sponges, echinoderms, mollusks, and
cephalochordates produce a variety of products with antifungal activity including bacterial …

Marine-derived natural lead compound disulfide-linked dimer psammaplin A: Biological activity and structural modification

Q Jing, X Hu, Y Ma, J Mu, W Liu, F Xu, Z Li, J Bai… - Marine drugs, 2019 - mdpi.com
Marine natural products are considered to be valuable resources that are furnished with
diverse chemical structures and various bioactivities. To date, there are seven compounds …

Hepatitis C virus NS3 inhibitors: current and future perspectives

KA Salam, N Akimitsu - BioMed research international, 2013 - Wiley Online Library
Currently, hepatitis C virus (HCV) infection is considered a serious health‐care problem all
over the world. A good number of direct‐acting antivirals (DAAs) against HCV infection are …

Marine-derived secondary metabolites as promising epigenetic bio-compounds for anticancer therapy

M Conte, E Fontana, A Nebbioso, L Altucci - Marine drugs, 2020 - mdpi.com
Sessile organisms such as seaweeds, corals, and sponges continuously adapt to both
abiotic and biotic components of the ecosystem. This extremely complex and dynamic …

[HTML][HTML] Chemical diversity and biological activities of marine-derived sulphur containing alkaloids: A comprehensive update

Z Zhang, Y Li, Y Sun, W Wang, X Song… - Arabian Journal of …, 2023 - Elsevier
Objectives The ocean is a huge ecosystem with diverse marine life. Scientists have found a
large number of natural products with unique structural features and excellent biological …

Natural allosteric modulators and their biological targets: molecular signatures and mechanisms

M Bruder, G Polo, DBB Trivella - Natural product reports, 2020 - pubs.rsc.org
Covering: 2008 to 2018 Over the last decade more than two hundred single natural products
were confirmed as natural allosteric modulators (alloNPs) of proteins. The compounds are …

Marine-Derived Bioactive Metabolites as a Potential Therapeutic Intervention in Managing Viral Diseases: Insights from the SARS-CoV-2 In Silico and Pre-Clinical …

QN Okechukwu, FO Adepoju, ON Kanwugu, P Adadi… - Pharmaceuticals, 2024 - mdpi.com
Worldwide urbanization and subsequent migration have accelerated the emergence and
spread of diverse novel human diseases. Among them, diseases caused by viruses could …

Recent Advancement in Anticancer Compounds from Marine Organisms: Approval, Use and Bioinformatic Approaches to Predict New Targets

G Santaniello, A Nebbioso, L Altucci, M Conte - Marine Drugs, 2022 - mdpi.com
In recent years, the study of anticancer bioactive compounds from marine sources has
received wide interest. Contextually, world regulatory authorities have approved several …