Of all the gynecologic tumors, ovarian cancer (OC) is known to be the deadliest. Advanced‐
stages of OC are linked with high morbidity and low survival rates despite the immense …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide
and has a poor prognosis. Current treatments for advanced NSCLC included traditional …

Background. Intrahepatic cholangiocarcinoma (ICC) is a subtype of primary liver cancer that
is rarely curable by surgery and is rapidly increasing in incidence. Relapsed ICC has a poor …

The epidermal growth factor receptor (EGFR) is a kind of receptor tyrosine kinase (RTK) that
plays a critical role in the initiation and development of malignant tumors via modulating …

Abstract The N-methyl-N′-nitroso-guanidine human osteosarcoma transforming gene
(MET) receptor tyrosine kinase and its ligand hepatocyte growth factor (HGF) control cellular …

Biliary tract cancer accounts for< 1% of all cancers and affects chiefly an elderly population,
with predominance in men. We distinguish cholangiocarcinoma (intrahepatic, hilar and …

Cholangiocarcinomas (CCAs) are diverse epithelial tumors arising from the liver or large
bile ducts with features of cholangiocyte differentiation. CCAs are classified anatomically …

Most of the patients with cholangiocarcinoma (CCA) present with advanced (inoperable or
metastatic) disease, and relapse rates are high in those undergoing potentially curative …

Glioblastomas multiforme (GBM) contain highly tumorigenic, self-renewing populations of
stem/initiating cells [glioblastoma stem cells (GSC)] that contribute to tumor propagation and …

Cholangiocarcinoma (CCA) is an aggressive biliary tract malignancy with limited treatment
options and low survival rates. Currently, there are no curative medical therapies for CCA …