Bone tumors, especially those in osteosarcoma, usually occur in adolescents. The standard
clinical treatment includes chemotherapy, surgical therapy, and radiation therapy …

Bone metastasis, a prevalent occurrence in primary malignant tumors, is often associated
with a grim prognosis. The bone microenvironment comprises various coexisting cell types …

Pharmaceuticals have been developed for the treatment of a wide range of bone diseases
and disorders, but suffer from problematic delivery to the bone marrow. Neutrophils are …

A variety of targeted nanoparticles were developed for the diagnosis and therapy of
orthotopic and metastatic bone tumors during the past decade. This critical review will focus …

Live cells have been vastly engineered into drug delivery vehicles to leverage their targeting
capability and cargo release behavior. Here, we describe a simple method to obtain …

Nanomaterials exhibit significant potential for stimulating immune responses, offering both
local and systemic modulation across a variety of diseases. The lymphoid organs, such as …

Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

Background Acute myeloid leukemia (AML) showed limited clinical therapeutic efficiency
with chemotherapy for its multi-distributed lesions and hard-to-kill leukemia cells deep in the …

Cancer cases have reached an all-time high in the current era. Thus, there is a need to
develop advanced therapeutic methods that can effectively inhibit the proliferation of …

Leukemia is a hematological malignancy associated with the uncontrolled proliferation of
mutant progenitors, suppressing the production of normal blood cells. Current treatments …