Antibiotic pollution in the environment: from microbial ecology to public policy
The ability to fight bacterial infections with antibiotics has been a longstanding cornerstone
of modern medicine. However, wide-spread overuse and misuse of antibiotics has led to …
of modern medicine. However, wide-spread overuse and misuse of antibiotics has led to …
Environmental factors influencing the development and spread of antibiotic resistance
J Bengtsson-Palme, E Kristiansson… - FEMS microbiology …, 2018 - academic.oup.com
Antibiotic resistance and its wider implications present us with a growing healthcare crisis.
Recent research points to the environment as an important component for the transmission …
Recent research points to the environment as an important component for the transmission …
A global atlas of the dominant bacteria found in soil
M Delgado-Baquerizo, AM Oliverio, TE Brewer… - Science, 2018 - science.org
The immense diversity of soil bacterial communities has stymied efforts to characterize
individual taxa and document their global distributions. We analyzed soils from 237 …
individual taxa and document their global distributions. We analyzed soils from 237 …
Nonnutritive sweeteners can promote the dissemination of antibiotic resistance through conjugative gene transfer
Antimicrobial resistance (AMR) poses a worldwide threat to human health and biosecurity.
The spread of antibiotic resistance genes (ARGs) via conjugative plasmid transfer is a major …
The spread of antibiotic resistance genes (ARGs) via conjugative plasmid transfer is a major …
[HTML][HTML] Geography, ethnicity or subsistence-specific variations in human microbiome composition and diversity
One of the fundamental issues in the microbiome research is characterization of the healthy
human microbiota. Recent studies have elucidated substantial divergences in the …
human microbiota. Recent studies have elucidated substantial divergences in the …
[PDF][PDF] The Prevotella copri complex comprises four distinct clades underrepresented in westernized populations
Prevotella copri is a common human gut microbe that has been both positively and
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …
negatively associated with host health. In a cross-continent meta-analysis exploiting> 6,500 …
DeepARG: a deep learning approach for predicting antibiotic resistance genes from metagenomic data
Background Growing concerns about increasing rates of antibiotic resistance call for
expanded and comprehensive global monitoring. Advancing methods for monitoring of …
expanded and comprehensive global monitoring. Advancing methods for monitoring of …
[HTML][HTML] Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance
There is growing understanding that the environment plays an important role both in the
transmission of antibiotic resistant pathogens and in their evolution. Accordingly …
transmission of antibiotic resistant pathogens and in their evolution. Accordingly …
Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge
Background There is concern that the microbially rich activated sludge environment of
wastewater treatment plants (WWTPs) may contribute to the dissemination of antibiotic …
wastewater treatment plants (WWTPs) may contribute to the dissemination of antibiotic …
[HTML][HTML] Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation
J Bengtsson-Palme, DGJ Larsson - Environment international, 2016 - Elsevier
There are concerns that selection pressure from antibiotics in the environment may
accelerate the evolution and dissemination of antibiotic-resistant pathogens. Nevertheless …
accelerate the evolution and dissemination of antibiotic-resistant pathogens. Nevertheless …