[HTML][HTML] The skin barrier: an extraordinary interface with an exceptional lipid organization

JA Bouwstra, A Nădăban, W Bras, C McCabe… - Progress in lipid …, 2023 - Elsevier
The barrier function of the skin is primarily located in the stratum corneum (SC), the
outermost layer of the skin. The SC is composed of dead cells with highly organized lipid …

Ceramides and skin function

L Coderch, O López, A de la Maza, JL Parra - American journal of clinical …, 2003 - Springer
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular
spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier …

FTIR microscopic imaging of collagen and proteoglycan in bovine cartilage

NP Camacho, P West, PA Torzilli… - … : Original Research on …, 2001 - Wiley Online Library
Articular cartilage, a connective tissue that provides resistance to compressive forces during
joint movements, has not been examined in detail by conventional Fourier transform infrared …

The use of synchrotron infrared microspectroscopy in biological and biomedical investigations

P Dumas, L Miller - Vibrational spectroscopy, 2003 - Elsevier
Synchrotron radiation is a bright source of infrared (IR) photons. It has been exploited in
microscopy, where much smaller areas can be probed, with sizes close to the diffraction …

The mechanism of skin lipids influencing skin status

Y Jia, Y Gan, C He, Z Chen, C Zhou - Journal of dermatological science, 2018 - Elsevier
Skin lipids, compose of sebocyte-, keratinocyte-, and microbe-derived lipids, dramatically
influence skin status by different mechanisms.(I) Physical chemistry function: They are …

[HTML][HTML] The permeability enhancing mechanism of DMSO in ceramide bilayers simulated by molecular dynamics

R Notman, WK den Otter, MG Noro, WJ Briels… - Biophysical journal, 2007 - cell.com
The lipids of the topmost layer of the skin, the stratum corneum, represent the primary barrier
to molecules penetrating the skin. One approach to overcoming this barrier for the purpose …

Ceramides in phospholipid membranes: effects on bilayer stability and transition to nonlamellar phases

MP Veiga, JLR Arrondo, FM Goni, A Alonso - Biophysical journal, 1999 - cell.com
The effects of ceramides of natural origin on the gel-fluid and lamellar-inverted hexagonal
phase transitions of phospholipids (mainly dielaidoylphosphatidylethanolamine) have been …

Vibrational spectroscopic studies of lipid domains in biomembranes and model systems

R Mendelsohn, DJ Moore - Chemistry and physics of lipids, 1998 - Elsevier
The Singer–Nicolson fluid mosaic model of membrane structure (Singer and Nicolson,
1972) depicting the lipid bilayer as a fluid, homogeneous solvent for membrane proteins has …

Intercellular and intracellular functions of ceramides and their metabolites in skin

HJ Cha, C He, H Zhao, Y Dong… - … journal of molecular …, 2016 - spandidos-publications.com
The skin consists of the epidermis, dermis and subcutis. The epidermis is primarily
comprised of keratinocytes and is separated into four layers according to the stage of …

[HTML][HTML] Is an orthorhombic lateral packing and a proper lamellar organization important for the skin barrier function?

D Groen, DS Poole, GS Gooris, JA Bouwstra - Biochimica et Biophysica …, 2011 - Elsevier
The lipid organization in the stratum corneum (SC), plays an important role in the barrier
function of the skin. SC lipids form two lamellar phases with a predominantly orthorhombic …