Cryptosporidium species has been identified as an important pediatric diarrheal pathogen in
resource-limited countries, particularly in very young children (0–24 months). However, the …

The role of malate dehydrogenase (MDH) in the metabolism of various medically significant
protozoan parasites is reviewed. MDH is an NADH-dependent oxidoreductase that …

In recent years, small molecule inhibition of LDHA (Lactate Dehydrogenase A) has evolved
as an appealing option for anticancer therapy. LDHA catalyzes the interconversion of …

Lactate dehydrogenase (LDH, EC 1.1. 1.27) is one of the vital glycolytic conditions,
especially during anaerobic conditions. It is a significant diagnostic, prognostic, and …

Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-Q), an
oxidative derivative of tire anti-degradant, has been linked to mortality in coho salmon …

Cancer cells exhibit an increased glycolysis rate for ATP generation (the Warburg effect) to
sustain an increased proliferation rate. In tumor cells, the oxidation of pyruvate in the Krebs …

The current study used the major target protein lactate dehydrogenase Cryptosporidium
parvum to identify potential binders. Our approach was a comprehensive three-step …

Abstract Cryptosporidium parvum (C. parvum), a protozoan parasite, is known to induce
significant gastrointestinal disease in humans. Lactate dehydrogenase (LDH), a protein of C …

The FIKK protein family, encompassing 21 serine-threonine protein kinases, is a distinctive
cluster exclusive to the Apicomplexa phylum. Predominantly located in Plasmodium …

Intestinal parasite infections, caused by intestinal helminths and protozoan parasites, are
prevalent diseases worldwide mainly transmitted through the fecal-oral route. The …