Chronic hepatitis B virus infection
Chronic hepatitis B virus infection is a global public health threat that causes considerable
liver-related morbidity and mortality. It is acquired at birth or later via person-to-person …
liver-related morbidity and mortality. It is acquired at birth or later via person-to-person …
[PDF][PDF] Guidance for design and endpoints of clinical trials in chronic hepatitis B—report from the 2019 EASL‐AASLD HBV Treatment Endpoints Conference
Representatives from academia, industry, regulatory agencies, and patient groups
convened in March 2019 with the primary goal of developing agreement on chronic hepatitis …
convened in March 2019 with the primary goal of developing agreement on chronic hepatitis …
A global scientific strategy to cure hepatitis B
PA Revill, FV Chisari, JM Block, M Dandri… - The lancet …, 2019 - thelancet.com
Chronic hepatitis B virus (HBV) infection is a global public health challenge on the same
scale as tuberculosis, HIV, and malaria. The International Coalition to Eliminate HBV (ICE …
scale as tuberculosis, HIV, and malaria. The International Coalition to Eliminate HBV (ICE …
[HTML][HTML] Safety, tolerability and antiviral activity of the antisense oligonucleotide bepirovirsen in patients with chronic hepatitis B: a phase 2 randomized controlled trial
Chronic infection with hepatitis B virus (HBV) leads to an increased risk of death from
cirrhosis and hepatocellular carcinoma. Functional cure rates are low with current treatment …
cirrhosis and hepatocellular carcinoma. Functional cure rates are low with current treatment …
[HTML][HTML] Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update
Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …
RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg
Chronic hepatitis B virus (HBV) infection is a major health concern worldwide, frequently
leading to liver cirrhosis, liver failure, and hepatocellular carcinoma. Evidence suggests that …
leading to liver cirrhosis, liver failure, and hepatocellular carcinoma. Evidence suggests that …
The changing epidemiology of liver diseases in the Asia–Pacific region
This Review presents current epidemiological trends of the most common liver diseases in
Asia–Pacific countries. Hepatitis B virus (HBV) remains the primary cause of cirrhosis; …
Asia–Pacific countries. Hepatitis B virus (HBV) remains the primary cause of cirrhosis; …
Hepatitis B virus infection
C Trépo, HLY Chan, A Lok - The Lancet, 2014 - thelancet.com
Hepatitis B virus infection is a major public health problem worldwide; roughly 30% of the
world's population show serological evidence of current or past infection. Hepatitis B virus is …
world's population show serological evidence of current or past infection. Hepatitis B virus is …
Occult hepatitis B infection and hepatocellular carcinoma: Epidemiology, virology, hepatocarcinogenesis and clinical significance
Occult hepatitis B infection (OBI) refers to a condition where replication-competent HBV DNA
is present in the liver, with or without HBV DNA in the blood, in individuals with serum …
is present in the liver, with or without HBV DNA in the blood, in individuals with serum …
Hepatitis B virus infection
MF Yuen, DS Chen, GM Dusheiko… - Nature reviews Disease …, 2018 - nature.com
Hepatitis B virus (HBV) is a hepatotropic virus that can establish a persistent and chronic
infection in humans through immune anergy. Currently, 3.5% of the global population is …
infection in humans through immune anergy. Currently, 3.5% of the global population is …