Skeletal muscle continuously adapts to changes in its mechanical environment through
modifications in gene expression and protein stability that affect its physiological function …

There are two components to the reperfusion syndrome, which follows extremity ischemia.
The local response, which follows reperfusion, consists of limb swelling with its potential for …

Ischemia reperfusion (IR) injury occurs when tissue is reperfused following a period of
ischemia, and results from acute inflammation involving various mechanisms. IR injury can …

Peripheral artery disease (PAD) is a common circulatory disorder of the lower limb arteries
that reduces functional capacity and quality of life of patients. Despite relatively effective …

BACKGROUND: Curcumin has been shown to decrease ischemia-reperfusion (I/R) injury in
kidney or brain tissues. In this study, the effects of curcumin were evaluated in skeletal …

Objectives: The aim of our study was to identify the risk factors associated with the
development of acute compartment syndrome (ACS) after a fracture of the tibia. Design …

Almost all orthopaedic surgeons come across acute compartment syndrome (ACS) in their
clinical practice. Diagnosis of ACS mostly relies on clinical findings. If the diagnosis is …

Acute compartment syndrome (ACS) is a surgical emergency. Diagnosis depends on a high
clinical suspicion and an understanding of risk factors, pathophysiology and subtle physical …

Background Extremity injury with ischaemia is the most common pattern of vascular trauma
and is a challenge for surgeons who must make decisions about the timing and mechanism …

Purpose Quantitative and qualitative changes of skeletal muscle are typical and early
findings in trauma patients, being possibly associated with functional impairment. Early …