Targeting prefrontal cortical dopamine D1 and N-methyl-D-aspartate receptor interactions in schizophrenia treatment

CR Yang, L Chen - The Neuroscientist, 2005 - journals.sagepub.com
The prefrontal cortex plays a principal role in higher cognition and particularly in the fast
online manipulation of appropriate information to guide forthcoming behavior. Dysfunction of …

N-methyl-D-aspartate antagonists as drug models of schizophrenia: a surprising link to tobacco smoking

EF Domino, D Mirzoyan, H Tsukada - Progress in Neuro …, 2004 - Elsevier
The pros and cons of N-methyl-d-aspartate (NMDA) antagonists as drug models of
schizophrenia are discussed in relation to the neuropathology of this complex mental …

Nicotine normalizes increased prefrontal cortical dopamine D1 receptor binding and decreased working memory performance produced by repeated pretreatment …

H Tsukada, K Miyasato, S Nishiyama… - …, 2005 - nature.com
The effects of acute nicotine were determined on dopamine (DA) D 1 (D 1 R) and D 2 (D 2
R) receptor binding in the neocortex of conscious monkeys under control conditions as well …