[HTML][HTML] Neurotoxicity of pesticides–A link to neurodegeneration

B Vellingiri, M Chandrasekhar, SS Sabari… - Ecotoxicology and …, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder which mainly targets motor
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …

Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease

M Tsalenchuk, SM Gentleman, SJ Marzi - npj Parkinson's Disease, 2023 - nature.com
Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …

Environmental risk factors and Parkinson's disease: an umbrella review of meta-analyses

V Bellou, L Belbasis, I Tzoulaki, E Evangelou… - Parkinsonism & related …, 2016 - Elsevier
Background Parkinson's disease is a neurological disorder with complex pathogenesis
implicating both environmental and genetic factors. We aimed to summarise the …

Environmental exposure to pesticides and the risk of Parkinson's disease in the Netherlands

M Brouwer, A Huss, M van der Mark, PCG Nijssen… - Environment …, 2017 - Elsevier
Background Exposure to pesticides has been linked to Parkinson's disease (PD), although
associations between specific pesticides and PD have not been well studied. Residents of …

A story of the potential effect of non-steroidal anti-inflammatory drugs (NSAIDs) in Parkinson's disease: beneficial or detrimental effects

M Alrouji, HM Al-Kuraishy, AI Al-Gareeb, HM Saad… - …, 2023 - Springer
Parkinson's disease (PD) is an advanced neurodegenerative disease (NDD) caused by the
degeneration of dopaminergic neurons (DNs) in the substantia nigra (SN). As PD is an age …

Exploring causality of the association between smoking and Parkinson's disease

V Gallo, P Vineis, M Cancellieri… - International journal …, 2019 - academic.oup.com
Background The aim of this paper is to investigate the causality of the inverse association
between cigarette smoking and Parkinson's disease (PD). The main suggested alternatives …

Epigenetic mechanisms in Parkinson's disease

Y Feng, J Jankovic, YC Wu - Journal of the neurological sciences, 2015 - Elsevier
Parkinson's disease (PD) is the second most common age-related neurodegenerative
disease, but its pathogenesis is not fully understood. The selective neuronal cell death in PD …

ROS networks: designs, aging, Parkinson's disease and precision therapies

A N. Kolodkin, RP Sharma, AM Colangelo… - NPJ systems biology …, 2020 - nature.com
How the network around ROS protects against oxidative stress and Parkinson's disease
(PD), and how processes at the minutes timescale cause disease and aging after decades …

Glitazone treatment and incidence of Parkinson's disease among people with diabetes: a retrospective cohort study

R Brauer, K Bhaskaran, N Chaturvedi, DT Dexter… - PLoS …, 2015 - journals.plos.org
Background Recent in vitro and animal experiments suggest that peroxisome proliferation-
activated receptor gamma (PPARɣ) agonist medications, such as antidiabetic glitazone …

The links between Parkinson's disease and cancer

M Ejma, N Madetko, A Brzecka, K Guranski, P Alster… - Biomedicines, 2020 - mdpi.com
Epidemiologic studies indicate a decreased incidence of most cancer types in Parkinson's
disease (PD) patients. However, some neoplasms are associated with a higher risk of …