This review highlights the use of functionalized organo-Li,-Mg and-Zn reagents for the
construction and selective functionalization of 5-and 6-membered fused bicyclic …

The aryl O-carbamate (ArOAm) group is among the strongest of the directed metalation
groups (DMGs) in directed ortho metalation (D o M) chemistry, especially in the form Ar …

Directed Ortho Metalation in 2021: A Tribute to Victor Snieckus (August 1, 1937–December 18,
2020) | Organic Process Research & Development ACS ACS Publications C&EN CAS Find my …

3-Phenylcoumarins are a family of heterocyclic molecules that are widely used in both
organic and medicinal chemistry. In this overview, research on this scaffold, since 2010, is …

Aryl and heteroaryl rings are omnipresent in small molecule drugs, and examples bearing
multiple substitutions at benzylic positions are ubiquitous across a range of pharmaceutical …

The regioselective functionalization of 7‐azaindole by controlled annular isomerism
employing a directed metalation‐group migration is reported. The N7 carbamoyl azaindoles …

The design and synthesis of novel heteroatom functionalized dienes competent to expand
the chemical space of the Diels–Alder cycloaddition reaction to prepare valuable yet …

Herein we report that readily available 4‐alkenylisocoumarins can be regarded as potent
dienolate equivalents. For example, lactol silyl ethers derived from 4‐alkenylisocoumarins …

Abstract The cross‐conjugated vinylogous [4+ 2] anionic annulation has been newly
developed, the cascade process of which has a high preference for regiochemical control …

Mono-and dianion species of 1, 8-naphthalene diamide 2 were generated under sec-
BuLi/TMEDA conditions and trapped with a variety of electrophiles to give 2-and 2, 7 …