Stroke-induced immunosuppression: implications for the prevention and prediction of post-stroke infections

J Faura, A Bustamante, F Miró-Mur… - Journal of …, 2021 - Springer
Stroke produces a powerful inflammatory cascade in the brain, but also a suppression of the
peripheral immune system, which is also called stroke-induced immunosuppression (SIIS) …

Immunodepression, infections, and functional outcome in ischemic stroke

WF Westendorp, C Dames, PJ Nederkoorn, A Meisel - Stroke, 2022 - Am Heart Assoc
Stroke remains one of the main causes of mortality and morbidity worldwide. Immediately
after stroke, a neuroinflammatory process starts in the brain, triggering a systemic …

The clinical value of neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), platelet-to-lymphocyte ratio (PLR) and systemic inflammation …

RH Wang, WX Wen, ZP Jiang, ZP Du, ZH Ma… - Frontiers in …, 2023 - frontiersin.org
Background Inflammatory mechanisms play important roles in intracerebral hemorrhage
(ICH) and have been linked to the development of stroke-associated pneumonia (SAP). The …

Post-stroke dysphagia: a review and design considerations for future trials

DL Cohen, C Roffe, J Beavan… - … Journal of Stroke, 2016 - journals.sagepub.com
Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive
complication of acute stroke and is associated with increased mortality, morbidity, and …

[HTML][HTML] Diagnosis of stroke-associated pneumonia

CJ Smith, AK Kishore, A Vail, A Chamorro, J Garau… - Stroke, 2015 - journals.lww.com
Lower respiratory tract infections frequently complicate stroke and adversely affect outcome.
There is currently no agreed terminology or gold-standard diagnostic criteria for the …

High neutrophil-to-lymphocyte ratio predicts stroke-associated pneumonia

KW Nam, TJ Kim, JS Lee, HM Kwon, YS Lee, SB Ko… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Although there are a variety of risk factors and predictive models
for stroke-associated pneumonia (SAP), more objective and easily accessible markers are …

Prophylactic antibiotics after acute stroke for reducing pneumonia in patients with dysphagia (STROKE-INF): a prospective, cluster-randomised, open-label, masked …

L Kalra, S Irshad, J Hodsoll, M Simpson, M Gulliford… - The Lancet, 2015 - thelancet.com
Background Post-stroke pneumonia is associated with increased mortality and poor
functional outcomes. This study assessed the effectiveness of antibiotic prophylaxis for …

Impact of dysphagia assessment and management on risk of stroke-associated pneumonia: a systematic review

SA Eltringham, K Kilner, M Gee, K Sage… - Cerebrovascular …, 2018 - karger.com
Background: Patients with dysphagia are at an increased risk of stroke-associated
pneumonia. There is wide variation in the way patients are screened and assessed during …

Stroke-induced immunodepression and dysphagia independently predict stroke-associated pneumonia–The PREDICT study

S Hoffmann, H Harms, L Ulm… - Journal of Cerebral …, 2017 - journals.sagepub.com
Stroke-associated pneumonia is a frequent complication after stroke associated with poor
outcome. Dysphagia is a known risk factor for stroke-associated pneumonia but …

Impact of stroke‐associated pneumonia on mortality, length of hospitalization, and functional outcome

WH Teh, CJ Smith, RS Barlas, AD Wood… - Acta Neurologica …, 2018 - Wiley Online Library
Objectives Stroke‐associated pneumonia (SAP) is common and associated with adverse
outcomes. Data on its impact beyond 1 year are scarce. Materials and methods This …