The application of next-generation sequencing to define factors related to oral cancer and discover novel biomarkers

S Kim, JW Lee, YS Park - Life, 2020 - mdpi.com
Despite the introduction of next-generation sequencing in the realm of DNA sequencing
technology, it is not often used in the investigation of oral squamous cell carcinoma (OSCC) …

Integrating cutting-edge methods to oral cancer screening, analysis, and prognosis

S Dholariya, RD Singh, A Sonagra… - Critical Reviews™ in …, 2023 - dl.begellhouse.com
Oral cancer (OC) has become a significant barrier to health worldwide due to its high
morbidity and mortality rates. OC is among the most prevalent types of cancer that affect the …

Worldwide prevalence of PI3K-AKT-mTOR pathway mutations in head and neck cancer: A systematic review and meta-analysis

AC de Moura, DX Assad, JA Dos Santos… - Critical Reviews in …, 2021 - Elsevier
A systematic review (SR) and meta-analysis were conducted to determine the prevalence of
PI3K-AKT-mTOR signaling pathway mutations in patients with head and neck cancer (HNC) …

Assessing long non-coding RNAs in tobacco-associated oral cancer

MK Mishra, S Gupta, Shivangi… - Current Cancer Drug …, 2022 - benthamdirect.com
Cancer is one of the compelling and pegged diseases battled by clinicians and researchers
worldwide. Among different types of cancer, oral cancer holds the sixth position globally …

Interaction of the tumor suppressor SMAD4 and WNT signaling in progression to oral squamous cell carcinoma

J Yang, JS Lewis, J Zi, T Andl, E Lee… - The Journal of …, 2024 - Wiley Online Library
SMAD4 is a tumor suppressor mutated or silenced in multiple cancers, including oral cavity
squamous cell carcinoma (OSCC). Human clinical samples and cell lines, mouse models …

[HTML][HTML] Genomic alterations in the stepwise progression from normal mucosa to metastasizing oral squamous cell carcinoma

JM Jensen, SMS Sjöstedt, JL Carmona… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction The aim of this study was to investigate the genomic changes that occur in the
development from dysplasia, cancer and to regional metastases in patients with oral cavity …

PDZ‐binding kinase inhibitor OTS514 suppresses the proliferation of oral squamous carcinoma cells

M Kato, A Ota, T Ono, S Karnan, T Hyodo… - Oral …, 2024 - Wiley Online Library
Objective PDZ‐binding kinase (PBK) has been reported as a poor prognostic factor and is a
promising molecular target for anticancer therapeutics. Here, we aimed to investigate the …

miR-10a-5p inhibits the migration and invasion of human oral carcinoma cells by targeting PIK3CA through PI3K/AKT/mTOR pathway.

R Tao, F Wang, X Feng, W Yang - Science Asia, 2022 - search.ebscohost.com
Oral carcinoma (OC) is one of the most common malignant tumors in the Chinese
population, and cancer metastasis is one of the leading causes of death in OC patients. This …

PIK3CA Hotspot Mutations in Saliva as a Diagnostic Marker in Oral Squamous Cell Carcinoma Patients

K Krüger, A Grust, D Muallah, A Patenge… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: This study aimed at the analogous detection of PIK3CA mutations,
common in oral squamous cell carcinoma (OSCC), in matched tumor and saliva samples …

[PDF][PDF] Nanopore sequencing technology in oral oncology: a comprehensive insight

D Augustine, SV Sowmya, VC Haragannavar, A Yousef… - Insight, 2022 - thejcdp.com
Aim: To review the principles and application of Nanopore Sequencing Technology (NPST)
in oral cancer. Background: Oral cancer is a disease caused by aberrations in the genes …