Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

Covering: up to the end of May 2011 Glyco (randomization/diversification) is a term that
encompasses strategies to diversify a core drug scaffold via enzymatic glycosylation to …

Aims This review is intended to update our previous discussion on the chemoenzymatic
synthesis of carbohydrates and glycoconjugates,(1) with new emphasis placed on …

In recent years, substantial advances have been made in the engineering of glycosidases
and glycosyltransferases for the synthesis and degradation of glycan structures. Key …

Catalysis is a key discipline in chemistry enabling clean and cost-efficient processes for a
large variety of different products and, therefore, has a strong economic impact in industry …

Remarkable advances have been made in recent years in exploiting the transglycosylation
activity of glycosidases and glycosynthase mutants for oligosaccharide and glycoconjugate …

Mammalian cell surfaces are all covered with bioactive oligosaccharides which play an
important role in molecular recognition events such as immune recognition, cell–cell …

In recent years, carbohydrate-processing enzymes have become the enzymes of choice in
many applications thanks to their stereoselectivity and efficiency. This review presents …

The ability to site-selectively modify equivalent functional groups in a molecule has the
potential to streamline syntheses and increase product yields by lowering step counts …

The many advances in glycoscience have more and more brought to light the crucial role of
glycosides and glycoconjugates in biological processes. Their major influence on the …