The alpha2-adrenergic receptor agonist Dexmedetomidine (Dex) is a sedative medication
used by anesthesiologists. Dex protects the heart against ischemia-reperfusion (IR) and can …

Background: Coronary artery disease is 2-3 times more common in diabetic individuals.
Dietary nitrate/nitrite has beneficial effects in both diabetes and cardiovascular disease. It …

Purpose Accumulating evidence indicates that intrauterine evolution disturbance can
contribute to myocardial ischemia reperfusion (IR) injury; in addition, thyroid hormones (THs) …

Introduction REM sleep deprivation (SD) decreases tolerance of the rat heart to ischemia-
reperfusion (IR) injury; the underlying mechanisms, however, are unknown. This study …

Ischemic postconditioning (IPost) is a strategy to provide protection against ischemia–
reperfusion (IR) injury. The cardioprotective effects of IPost in cases of ischemic heart …

Objective Increased renal and hepatic gluconeogenesis are important sources of fasting
hyperglycemia in type 2 diabetes (T2D). The inhibitory effect of co-administration of sodium …

Aging is associated with increased prevalence of cardiovascular disease. Thyroid hormone
deficiency during fetal life decreases myocardial tolerance to ischemia-reperfusion (IR) …

Cardioprotection by ischemic postconditioning (IPost) is negated in hypothyroidism; the
underlying mechanisms however are unknown. This study aimed at determining whether …

Background: Sleep deprivation (SD) is strongly associated with elevated risk for
cardiovascular disease. Objective: To determine the effect of SD on basal hemodynamic …

Accepted: 1 Dec. 2020 There is a reciprocal regulation of arginase and nitric oxide synthase
in L-arginine metabolizing pathways. Nitric oxide has been claimed as an important role …