The Mediator complex is a multi-subunit assembly that appears to be required for regulating
expression of most RNA polymerase II (pol II) transcripts, which include protein-coding and …

Saccharomyces cerevisiae preferentially uses glucose as a carbon source, but following its
depletion, it can utilize a wide variety of other carbons including nonfermentable compounds …

Temporal control of heterologous pathway expression is critical to achieve optimal efficiency
in microbial metabolic engineering. The broadly-used GAL promoter system for engineered …

The transcription factors Adr1 and Cat8 act in concert to regulate the expression of
numerous yeast genes after the diauxic shift. Their activities are regulated by Snf1, the yeast …

Cell signaling regulates several physiological processes by receiving, processing, and
transmitting signals between the extracellular and intracellular environments. In signal …

The paradigm of activation via ordered recruitment has evolved into a complicated picture as
the influence of coactivators and chromatin structures on gene regulation becomes …

A cell's reaction to any change in the endogenous or exogenous conditions often involves a
complex response that eventually either leads to cell adaptation and survival or to the …

Alcohol consumption is a risk factor for oral cancer, possibly via its conversion to
acetaldehyde, a known carcinogen. The oral commensal yeast Candida albicans may be …

In eukaryotes combinatorial activation of transcription is an important component of gene
regulation. In the budding yeast Saccharomyces cerevisiae, Adr1-Cat8 and Adr1-Oaf1/Pip2 …

In the yeast Saccharomyces cerevisiae, the switch from respiratory metabolism to
fermentation causes rapid decay of transcripts encoding proteins uniquely required for …