Gastrin, cholecystokinin and gastrointestinal tract functions in mammals

P Guilloteau, V Le Meuth-Metzinger… - Nutrition research …, 2006 - cambridge.org
The aim of the present review is to synthesise and summarise our recent knowledge on the
involvement of cholecystokinin (CCK) and gastrin peptides and their receptors in the control …

Neurohormonal regulation of histamine and pancreastatin secretion from isolated rat stomach ECL cells

E Lindström, M Björkqvist, Å Boketoft, D Chen… - Regulatory peptides, 1997 - Elsevier
ECL cells are numerous in the acid-producing part of the rat stomach. They are rich in
histamine and pancreastatin, a chromogranin A-derived peptide, and they secrete these …

The biology and pathobiology of the ECL cells.

R Håkanson, Y Tielemans, D Chen… - The Yale Journal of …, 1992 - ncbi.nlm.nih.gov
The enterochromaffin-like (ECL) cells represent the predominant endocrine cell population
in the acid-producing part of the stomach of both experimental animals and man. These cells …

A model for integrative study of human gastric acid secretion

IMP Joseph, Y Zavros, JL Merchant… - Journal of applied …, 2003 - journals.physiology.org
We have developed a unique virtual human model of gastric acid secretion and its
regulation in which food provides a driving force. Food stimulus triggers neural activity in …

Gastrin regulates histidine decarboxylase activity and mRNA abundance in rat oxyntic mucosa

AK Sandvik, R Dimaline, R Marvik… - American Journal …, 1994 - journals.physiology.org
Gastrin release histamine from the oxyntic mucosa, stimulates the enzymatic activity of
histidine decarboxylase (HDC), increases HDC mRNA abundance, and has a trophic effect …

Pharmacological analysis of CCK2 receptor antagonists using isolated rat stomach ECL cells

E Lindström, M Björkqvist… - British journal of …, 1999 - Wiley Online Library
Gastrin stimulates rat stomach ECL cells to secrete histamine and pacreastatin, a
chromogranin A (CGA)‐derived peptide. The present report describes the effect of nine …

A model for the study of Helicobacter pylori interaction with human gastric acid secretion

IM Joseph, D Kirschner - Journal of Theoretical Biology, 2004 - Elsevier
We present a comprehensive mathematical model describing Helicobacter pylori interaction
with the human gastric acid secretion system. We use the model to explore host and …

Long‐lasting cholecystokinin2 receptor blockade after a single subcutaneous injection of YF476 or YM022

M Kitano, P Norlén, XQ Ding… - British journal of …, 2000 - Wiley Online Library
Histamine‐forming ECL cells in the rat stomach operate under the control of gastrin. They
represent a convenient target for studying cholecystokinin‐B/gastrin (CCK2) receptor …

Effect of cholecystokinin and secretin on somatostatin release from cultured antral cells

YN Kwok, AMJ Buchan, RM Meloche, H Kofod - Gastroenterology, 1993 - Elsevier
Abstract Background: Both secretin and Cholecystokinin (CCK) inhibit gastric acid secretion.
However, their mode of action has yet to be determined. A newly developed primary culture …

Role of gastrin in the development of gastric mucosa, ECL cells and A-like cells in newborn and young rats

M Björkqvist, CD de la Cour, CM Zhao… - Regulatory peptides, 2002 - Elsevier
Histamine-producing ECL cells and ghrelin-producing A-like cells are endocrine/paracrine
cell populations in the acid-producing part of the rat stomach. While the A-like cells operate …