The endothelium maintains vascular homeostasis through the release of active vasodilators.
Although nitric oxide (NO) is recognized as the primary factor at level of conduit arteries …

Background: A large yet heterogeneous body of literature exists suggesting that endothelial
dysfunction appears early in type 1 diabetes, due to hyperglycemia-induced oxidative stress …

Internal elastic lamina (IEL) hole (fenestration) characteristics and myoendothelial gap
junction (MEGJ) density were examined in selected resistance and conduit arteries of …

Roselle (Hibiscus sabdariffa) is reported to be beneficial in treating obesity which can
develop into a range of metabolic disorders. The molecular mechanisms by which roselle …

The present study evaluated the anti-obesity properties of papaya in high-fat (HF) diet fed
rats. In the in vitro portion of the present study, the effects of papaya juice on pancreatic …

Serelaxin prevents endothelial dysfunction in the mouse aorta ex vivo and inhibits apoptosis
in cardiomyocytes under acute hyperglycaemia. Less is known about the effects of serelaxin …

Hypercholesterolaemia is associated with oxidative stress and endothelial dysfunction and
leads to the development of atherosclerosis. Naringin exhibits cardiovascular protective and …

Endothelial dysfunction is characterized by reduced bioavailability of NO due to its
inactivation to form peroxynitrite or reduced expression of eNOS. Here, we examine the …

Endothelial cell injury is an essential component of atherosclerosis and hypertension.
Atherosclerosis and other macrovascular diseases are the most common complications of …

Background The majority of studies have investigated the effect of exercise training (TR) on
vascular responses in diabetic animals (DB), but none evaluated nitric oxide (NO) and …