The pivotal observation that muscular exercise is associated with oxidative stress in humans
was first reported over 45 years ago. Soon after this landmark finding, it was discovered that …

Exercise‐induced benefits are being increasingly recognized in promoting health and
preventing diseases. However, initial adaption to exercise response can have different …

Myocardial infarction (MI)-induced heart failure (HF) is commonly accompanied with
profound effects on skeletal muscle. With the process of MI-induced HF, perturbations in …

Exercise training has been reported to alleviate cardiac fibrosis and ameliorate heart
dysfunction after myocardial infarction (MI), but the molecular mechanism is still not fully …

Medical advances and the availability of diagnostic tools have considerably increased life
expectancy and, consequently, the elderly segment of the world population. As age is a …

Growing evidence has demonstrated exercise as an effective way to promote cardiovascular
health and protect against cardiovascular diseases However, the underlying mechanisms of …

Rheumatoid arthritis (RA) is a common systematic, chronic inflammatory, autoimmune, and
polyarticular disease, causing a range of clinical manifestations, including joint swelling …

It has been proven that physical exercise improves cognitive function and memory, has an
analgesic and antidepressant effect, and delays the aging of the brain and the development …

Sarcopenia, a syndrome commonly seen in elderly populations, is often characterized by a
gradual loss of skeletal muscle, leading to the decline of muscle strength and physical …

Skeletal muscle mass and function tend to decline with increasing age. Insulin-like growth
factor 1 (IGF-1) plays a key role in promoting skeletal muscle growth. Exercise improves …