Lysine demethylase inhibitors for myeloproliferative disorders

JA Baker, JC Palomino, MCT Fyfe, T Maes… - US Patent …, 2018 - Google Patents
The invention relates to methods and compositions for the treatment or prevention of
diseases and disorders associated with myeloproliferative disorders. In particular, the …

Lysine demethylase inhibitors for diseases and disorders associated with Hepadnaviridae

JA Baker, MCT Fyfe - US Patent 9,186,337, 2015 - Google Patents
The present invention provides for the treatment or prevention of Hepadnaviridae infection
and disease caused by Hepadnaviridae infection. In particular, the invention provides …

Phenylcyclopropylamine derivatives and their medical use

N Guibourt, AO Munoz, JCP Laria - US Patent 8,993,808, 2015 - Google Patents
US8993808B2 - Phenylcyclopropylamine derivatives and their medical use - Google
Patents US8993808B2 - Phenylcyclopropylamine derivatives and their medical use …

Lysine specific demethylase-1 inhibitors and their use

AO Muñoz, JCP Laria, MCT Fyfe - US Patent 8,859,555, 2014 - Google Patents
The invention relates to a compound of Formula (I):(A)-(A)-(B)-(Z)-(L)-(D), wherein:(A) is
heteroaryl or aryl; each (A'), if present, is independently chosen from aryl, aryla lkoxy …

Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use

AO Muñoz, MCT Fyfe, MM Pedemonte… - US Patent …, 2015 - Google Patents
Int. C. C07D 285/12 C07D 27L/12 CO7D 263/02 C07D 275/02 CO7D 26/02 CO7D 239/42
A6 IK3I/433 A6 IK3I/4245 A6 IK3I/422 C07D 213/73 C07D 237/20 CO7D 24/20 C07D …

Cyclopropaneamine compound

N Tomita, S Kajii, DR Cary, D Tomita… - US Patent …, 2016 - Google Patents
The present invention provides a compound having a lysine specific demethylase 1
inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for …

Lysine specific demethylase-1 inhibitors and their use

AO Muñoz, JCP Laria, MCT Fyfe - US Patent 9,149,447, 2015 - Google Patents
The present invention relates to a compound of Formula 1, wherein:(A) is heteroaryl or aryl;
each (A'), if present, is independently chosen from aryl, arylalkoxy, arylalkyl, het erocyclyl …

Cyclopropylamine derivatives useful as LSD1 inhibitors

MCT Fyfe, AO Muñoz, JCP Laria… - US Patent …, 2015 - Google Patents
2013-08-30 Assigned to ORYZON GENOMICS SA reassignment ORYZON GENOMICS SA
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Lysine demethylase inhibitors for diseases and disorders associated with Flaviviridae

JA Baker, MCT Fyfe - US Patent 9,790,196, 2017 - Google Patents
US9790196B2 - Lysine demethylase inhibitors for diseases and disorders associated with
Flaviviridae - Google Patents US9790196B2 - Lysine demethylase inhibitors for diseases and …

Cyclopropanamine compound and use thereof

N Tomita, D Tomita, Y Tominari, S Imamura… - US Patent …, 2017 - Google Patents
2015-04-13 Assigned to TAKEDA PHARMACEUTICAL COMPANY LIMITED reassignment
TAKEDA PHARMACEUTICAL COMPANY LIMITED ASSIGNMENT OF ASSIGNORS …