RNA-binding proteins (RBPs) are central players in post-transcriptional regulation and
immune homeostasis. The ribonuclease and RBP Regnase-1 exerts critical roles in both …

Simple Summary Chronic inflammatory diseases account for up to 60% of deaths worldwide
and, thus, are considered a great threat for human health by the World Health Organization …

Cathelicidin LL-37 plays an essential role in innate immunity by killing invading
microorganisms and regulating the inflammatory response. These activities depend on the …

Pattern recognition receptors are critical for the detection of invading microorganisms. They
activate multiple pathways that lead to the induction of proinflammatory responses and …

Fungal keratitis (FK) is a serious corneal infection caused by pathogenic fungi. Monocyte
chemoattractant protein-induced protein 1 (MCPIP1) plays an important role in restricting the …

Sterile inflammation either resolves the initial insult or leads to tissue damage. Kidney
ischemia/reperfusion injury (IRI) is associated with neutrophilic infiltration, enhanced …

Kaposi's sarcoma-associated herpesvirus (KSHV), the causative agent of Kaposi's sarcoma,
encodes 25 mature viral miRNAs. MCP-1-induced protein-1 (MCPIP1), a critical regulator of …

Objectives The purposes of this study were to localize monocyte chemoattractant protein-1-
induced protein-1 (MCPIP-1) and its suppressor mucosa-associated lymphoid tissue …

Background A universal adaptor protein, MyD88, orchestrates the innate immune response
by propagating signals from toll-like receptors (TLRs) and interleukin-1 receptor (IL-1R) …

Monocyte chemoattractant protein-induced protein 1 (MCPIP1), also called Regnase-1, is an
RNase that has been described as a key negative modulator of inflammation. MCPIP1 also …