Nimbolide, a major limonoid constituent of Azadirachta indica, commonly known as neem,
has attracted increasing research attention owing to its wide spectrum of pharmacological …

Cancer is a major cause of death worldwide with an increasing incidence rate and is
considered a major public health problem. Distance metastasis to other tissues, high toxicity …

Fungal endophytes are known to be a paragon for producing bioactive compounds with a
variety of pharmacological importance. The current study aims to elucidate the molecular …

Along with direct anticancer activity, curcumin hinders the onset of chemoresistance. Among
many, high glucose condition is a key driving factor for chemoresistance. However, the …

Abstract Cyclic nucleotide phosphodiesterase 5 (PDE5) has been recently identified to play
a crucial role in the progression of many cancers. PDE5 promotes tumorigenesis by …

Synthesis of the azo–Schiff base ligands 2-((E)-((4-(diethylamino) phenyl) imino) methyl)-4-
((E)-(2-(phenylthio) phenyl) diazenyl) phenol (L1) and-((E)-((4-(diethylamino) phenyl)-imino) …

Abstract Background Prostate cancer (PCa) is the most prominent malignancy among men
worldwide. PCa cells have a high tendency to metastasize to various distant organs, and this …

Chemotherapy is a life-sustaining therapeutic option for cancer patients. Despite the
advancement of several modern therapies, such as immunotherapy, gene therapy, etc …

Exploring the therapeutic potential of Neem (Azadirachta Indica) for the treatment of prostate
cancer: a literature review - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Nimbolide is reported as one of the potential anticancer candidates of the neem tree
(Azadirachta indica A. Juss). The cytotoxic action of nimbolide has been well reported …