Streptococcus pneumoniae (pneumococcus) is an important pathogen responsible for acute
invasive and non-invasive infections such as meningitis, sepsis and otitis media, being the …

Bacteria possess the ability to evolve varied and ingenious strategies to outwit the host
immune system, instigating an evolutionary arms race. Proteases are amongst the many …

Manganese (Mn) is an essential micronutrient and required cofactor in bacteria. Despite its
importance, excess Mn can impair bacterial growth, the mechanism of which remains largely …

Bacteria live in a polymicrobial community where it interacts with biotic and abiotic factors
using specific signalling molecules. Acyl homoserine lactones, autoinducing peptides …

Streptococcus suis is an emerging zoonotic pathogen that causes severe swine and human
infections. Metals are essential nutrients for life; however, excess metals are toxic to …

Existing capsular polysaccharide‐based vaccines against pneumococcal disease are highly
effective against vaccine‐included serotypes, but they are unable to combat serotype …

By using a transcriptomic approach, we have elucidated the effect of Ni2+ on the global
gene expression of S. pneumoniae D39 by identifying several differentially expressed …

In this study, we investigated the transcriptomic response of Streptococcus pneumoniae D39
to cysteine. Transcriptome comparison of the D39 wild-type grown at a restricted …

The pathology associated with human respiratory tract bacterial agents that exist as
opportunistic commensals in the nasopharynx cause infections. This is particularly true for …

Streptococcus pneumoniae is one of the leading human pathogen causing morbidity and
mortality worldwide. The pneumococcus can cause a variety of different diseases ranging …