The scaffold-forming steps of plant alkaloid biosynthesis

BR Lichman - Natural Product Reports, 2021 - pubs.rsc.org
Alkaloids from plants are characterised by structural diversity and bioactivity, and maintain a
privileged position in both modern and traditional medicines. In recent years, there have …

Same substrate, many reactions: oxygen activation in flavoenzymes

E Romero, JR Gómez Castellanos, G Gadda… - Chemical …, 2018 - ACS Publications
Over time, organisms have evolved strategies to cope with the abundance of dioxygen on
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …

Large-scale whole-genome resequencing unravels the domestication history of Cannabis sativa

G Ren, X Zhang, Y Li, K Ridout… - Science …, 2021 - science.org
Cannabis sativa has long been an important source of fiber extracted from hemp and both
medicinal and recreational drugs based on cannabinoid compounds. Here, we investigated …

Natural history–guided omics reveals plant defensive chemistry against leafhopper pests

Y Bai, C Yang, R Halitschke, C Paetz, D Kessler… - Science, 2022 - science.org
Although much is known about plant traits that function in nonhost resistance against
pathogens, little is known about nonhost resistance against herbivores, despite its …

Formation and cleavage of C–C bonds by enzymatic oxidation–reduction reactions

FP Guengerich, FK Yoshimoto - Chemical Reviews, 2018 - ACS Publications
Many oxidation–reduction (redox) enzymes, particularly oxygenases, have roles in reactions
that make and break C–C bonds. The list includes cytochrome P450 and other heme-based …

Breaking bad news: dynamic molecular mechanisms of wound response in plants

I Vega-Muñoz, D Duran-Flores… - Frontiers in plant …, 2020 - frontiersin.org
Recognition and repair of damaged tissue are an integral part of life. The failure of cells and
tissues to appropriately respond to damage can lead to severe dysfunction and disease …

Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases

JD Rudolf, CY Chang - Natural product reports, 2020 - pubs.rsc.org
Covering: up to July 2019 Terpene synthases (TSs) are responsible for generating much of
the structural diversity found in the superfamily of terpenoid natural products. These elegant …

Extracellular DAMPs in plants and mammals: immunity, tissue damage and repair

G De Lorenzo, S Ferrari, F Cervone, E Okun - Trends in immunology, 2018 - cell.com
Innate immune receptors, well known mediators of response to non-self-molecules and
inflammation, also act as mediators of immunity triggered by 'damage-associated molecular …

How Does Phytophthora infestans Evade Control Efforts? Modern Insight Into the Late Blight Disease

W Leesutthiphonchai, AL Vu, AMV Ah-Fong… - …, 2018 - Am Phytopath Society
The infamous oomycete Phytophthora infestans has been a persistent threat to potato and
tomato production worldwide, causing the diseases known as late blight. This pathogen has …

Four Arabidopsis berberine bridge enzyme‐like proteins are specific oxidases that inactivate the elicitor‐active oligogalacturonides

M Benedetti, I Verrascina, D Pontiggia, F Locci… - The Plant …, 2018 - Wiley Online Library
Recognition of endogenous molecules acting as 'damage‐associated molecular
patterns'(DAMPs) is a key feature of immunity in both animals and plants …