Insulin resistance and cardiovascular disease

CE Kosmas, MD Bousvarou… - Journal of …, 2023 - journals.sagepub.com
Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …

[HTML][HTML] Glycolipid metabolic disorders, metainflammation, oxidative stress, and cardiovascular diseases: unraveling pathways

EP de Lima, RC Moretti Jr, K Torres Pomini… - Biology, 2024 - mdpi.com
Simple Summary Glycolipid metabolic disorders (GLMDs) result from imbalances in
glycolipid levels, leading to various health issues, including obesity, diabetes, liver …

Mapping the effectiveness and risks of GLP-1 receptor agonists

Y Xie, T Choi, Z Al-Aly - Nature Medicine, 2025 - nature.com
Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are increasingly being used to treat
diabetes and obesity. However, their effectiveness and risks have not yet been …

[HTML][HTML] Vascular impairment, muscle atrophy, and cognitive decline: Critical age-related conditions

EP de Lima, M Tanaka, CB Lamas, K Quesada… - Biomedicines, 2024 - mdpi.com
The triad of vascular impairment, muscle atrophy, and cognitive decline represents critical
age-related conditions that significantly impact health. Vascular impairment disrupts blood …

Insights into pathogenesis, nutritional and drug approach in sarcopenia: a systematic review

RH Mellen, OS Girotto, EB Marques, LF Laurindo… - Biomedicines, 2023 - mdpi.com
Sarcopenia is a multifactorial condition related to the loss of muscle mass and strength due
to aging, eating habits, physical inactivity, or even caused by another disease. Affected …

Incretin-based drugs as potential therapy for neurodegenerative diseases: current status and perspectives

F Ferrari, A Moretti, RF Villa - Pharmacology & therapeutics, 2022 - Elsevier
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most frequent
neurodegenerative disorders. Despite their pathophysiological and clinical differences, they …

The role of glucagon-like peptide-1 receptor agonists (GLP-1 RA) in diabetes-related neurodegenerative diseases

D Cheng, S Yang, X Zhao, G Wang - Drug design, development …, 2023 - Taylor & Francis
Recent clinical guidelines have emphasized the importance of screening for cognitive
impairment in older adults with diabetes, however, there is still a lack of understanding about …

Protection against stroke with glucagon-like peptide-1 receptor agonists: a comprehensive review of potential mechanisms

B Vergès, V Aboyans, D Angoulvant… - Cardiovascular …, 2022 - Springer
Several randomized controlled trials have demonstrated the benefits of glucagon-like
peptide-1 receptor agonists (GLP-1RAs) on ischemic stroke in patients with diabetes. In this …

Glucagon-like peptide-1 receptor agonist use and residual gastric content before anesthesia

S Sen, PP Potnuru, N Hernandez, C Goehl… - JAMA …, 2024 - jamanetwork.com
Importance Glucagon-like peptide-1 receptor agonist (GLP-1 RA) use is rapidly increasing in
the US, driven by its expanded approval for weight management in addition to …

The mechanism and efficacy of GLP-1 receptor agonists in the treatment of Alzheimer's disease

H Du, X Meng, Y Yao, J Xu - Frontiers in Endocrinology, 2022 - frontiersin.org
Since type 2 diabetes mellitus (T2DM) is a risk factor for Alzheimer's disease (AD) and both
have the same pathogenesis (eg, insulin resistance), drugs used to treat T2DM have been …