To eliminate tuberculosis globally, a new, effective, and affordable vaccine is urgently
needed, particularly for use in adults and adolescents in low-income and middle-income …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …

Mathematical modelling and statistical inference provide a framework to evaluate different
non-pharmaceutical and pharmaceutical interventions for the control of epidemics that has …

There is global consensus on the urgent need for a safe and effective TB vaccine for adults
and adolescents to improve global TB control, and encouragingly, several promising …

We investigated the effects of updating age-specific social contact matrices to match
evolving demography on vaccine impact estimates. We used a dynamic transmission model …

High tuberculosis (TB) burden countries (HBCs) need to prepare for TB vaccine
implementation alongside licensure, to ensure rapid rollout. WHO policy/implementation …

This ECVP is a new technical product that aims to anticipate and collectively delineate the
clinical trial, observational and other data likely to be required by global and national policy …

Background: Tuberculosis is a leading cause of death worldwide from a single infectious
agent, with an estimated 10.6 million new cases and 1.6 million deaths in 2021. The global …

La Tuberculosis (TB) ha estado presente en todos los territorios del planeta, segando la
vida de millones de personas. El descubrimiento de los primeros antibióticos, el desarrollo …

Since thousands of years ago, the long shadow of Tuberculosis (TB) has tormented
humanity, slowly, but constantly, decimating human civilisations. This old disease, caused …