[HTML][HTML] Synonymous nucleotide changes drive papillomavirus evolution

KM King, EV Rajadhyaksha, IG Tobey… - Tumour Virus …, 2022 - Elsevier
Papillomaviruses have been evolving alongside their hosts for at least 450 million years.
This review will discuss some of the insights gained into the evolution of this diverse family …

Embracing Complexity: What Novel Sequencing Methods Are Teaching Us About Herpesvirus Genomic Diversity

A Ortigas-Vasquez, M Szpara - Annual Review of Virology, 2024 - annualreviews.org
The arrival of novel sequencing technologies throughout the past two decades has led to a
paradigm shift in our understanding of herpesvirus genomic diversity. Previously …

Evolutionary Dynamics of Accelerated Antiviral Resistance Development in Hypermutator Herpesvirus

T Höfler, MM Nascimento, M Zeitlow… - Molecular Biology …, 2024 - academic.oup.com
Antiviral therapy is constantly challenged by the emergence of resistant pathogens. At the
same time, experimental approaches to understand and predict resistance are limited by …

Viral shedding 1 year following first-episode genital HSV-1 infection

C Johnston, A Magaret, H Son, M Stern, M Rathbun… - Jama, 2022 - jamanetwork.com
Importance Herpes simplex virus type 1 (HSV-1) is the leading cause of first-episode genital
herpes in many countries. Objective To inform counseling messages regarding genital HSV …

Intra-host genomic diversity and integration landscape of human tissue-resident DNA virome

L Pyöriä, D Pratas, M Toppinen… - Nucleic Acids …, 2024 - academic.oup.com
The viral intra-host genetic diversities and interactions with the human genome during
decades of persistence remain poorly characterized. In this study, we analyzed the …

Phylogenetic and genomic characterization of whole genome sequences of ocular herpes simplex virus type 1 isolates identifies possible virulence determinants in …

VQ Chau, AW Kolb, DL Miller… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: There are limited data on the prevalence and genetic diversity of herpes simplex
virus type 1 (HSV-1) virulence genes in ocular isolates. Here, we sequenced 36 HSV-1 …

Multi-phenotype analysis for enhanced classification of 11 herpes simplex virus 1 strains

SN Dweikat, DW Renner… - Journal of General …, 2022 - microbiologyresearch.org
Herpes simplex virus 1 (HSV1) is best known for causing oral lesions and mild clinical
symptoms, but it can produce a significant range of disease severities and rates of …