Endoplasmic reticulum architecture and inter-organelle communication in metabolic health and disease

AP Arruda, G Parlakgül - Cold Spring Harbor …, 2023 - cshperspectives.cshlp.org
The endoplasmic reticulum (ER) is a key organelle involved in the regulation of lipid and
glucose metabolism, proteostasis, Ca2+ signaling, and detoxification. The structural …

Membrane shape and the regulation of biological processes

JC Bozelli Jr, RM Epand - Journal of molecular biology, 2020 - Elsevier
Biological membranes define and determine the architecture, ie, shape, of cells and
organelles. While most membranes present a planar morphology on the nanometer length …

Excess diacylglycerol at the endoplasmic reticulum disrupts endomembrane homeostasis and autophagy

D Li, SG Yang, CW He, ZT Zhang, Y Liang, H Li, J Zhu… - BMC biology, 2020 - Springer
Background When stressed, eukaryotic cells produce triacylglycerol (TAG) to store nutrients
and mobilize autophagy to combat internal damage. We and others previously reported that …

A novel automated image analysis pipeline for quantifying morphological changes to the endoplasmic reticulum in cultured human cells

ME Garcia-Pardo, JC Simpson, NC O'Sullivan - BMC bioinformatics, 2021 - Springer
Background In mammalian cells the endoplasmic reticulum (ER) comprises a highly
complex reticular morphology that is spread throughout the cytoplasm. This organelle is of …

Lung epithelial endoplasmic reticulum and mitochondrial 3D ultrastructure: a new frontier in lung diseases

SR Bruno, V Anathy - Histochemistry and Cell Biology, 2021 - Springer
It has long been appreciated that the endoplasmic reticulum (ER) and mitochondria,
organelles important for regular cell function and survival, also play key roles in …

Reproductive cycle of sea urchin Echinometra vanbrunti (Echinodermata: Echinoidea) from the Gulf of California

AG Villalba Villalba, LH Chan Chan… - Marine Biology …, 2021 - Taylor & Francis
Echinometra vanbrunti is an echinoid found in abundance in the eastern Pacific, including
the Gulf of California in Mexico. The aim of this study is to document its annual reproductive …

Tubular ER associates with diacylglycerol-rich structures during lipid droplet consumption

S Ganesan, M Tavassoli, BN Shabits… - Frontiers in Cell and …, 2020 - frontiersin.org
Growth resumption from stationary phase in Saccharomyces cerevisiae, is characterized by
lipid droplet (LD) consumption and channeling of lipid precursors toward synthesis of …

[PDF][PDF] Beyond Membrane Curvature: Clade 6 Reticulons and Their Role Within the Plant Endoplasmic Reticulum

S Wojcik, V Kriechbaumer, P Moreau - 2021 - radar.brookes.ac.uk
The endoplasmic reticulum (ER) is a dynamic organelle with multiple functions. It is
comprised of distinct morphological domains. Regulation of this morphology and its …