Inflammatory processes involved in NASH-related hepatocellular carcinoma

S Cannito, U Dianzani, M Parola, E Albano… - Bioscience …, 2023 - portlandpress.com
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death
worldwide. In the recent years nonalcoholic fatty liver disease (NAFLD) is becoming a …

Macrophages and the development and progression of non-alcoholic fatty liver disease

B Alabdulaali, F Al-Rashed, M Al-Onaizi… - Frontiers in …, 2023 - frontiersin.org
The liver is the site of first pass metabolism, detoxifying and metabolizing blood arriving from
the hepatic portal vein and hepatic artery. It is made up of multiple cell types, including …

Effects of cholesterol on biomolecular corona

N Mahmoudi, M Mahmoudi - Nature Nanotechnology, 2023 - nature.com
Effects of cholesterol on biomolecular corona | Nature Nanotechnology Skip to main content
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ACOD1 deficiency offers protection in a mouse model of diet-induced obesity by maintaining a healthy gut microbiota

T Eberhart, FU Stanley, L Ricci, T Chirico… - Cell Death & …, 2024 - nature.com
Abstract Aconitate decarboxylase 1 (ACOD1) is the enzyme synthesizing itaconate, an
immuno-regulatory metabolite tuning host-pathogen interactions. Such functions are …

Etiology of end-stage liver cirrhosis impacts hepatic natural killer cell heterogenicity

AC Maretti-Mira, MP Salomon, AM Hsu, L Dara… - Frontiers in …, 2023 - frontiersin.org
The natural killer (NK) cell population is a critical component of the innate immune
compartment of the liver, and its functions are deeply affected by the surrounding …

[HTML][HTML] High cholesterol disorders, myocardial infarction and its therapeutics

RK Upadhyay - World Journal of Cardiovascular Diseases, 2023 - scirp.org
The current review article discusses several conditions linked to high cholesterol, including
their causes, diagnoses, and treatments. Cardiovascular disease is one of the leading …

Longitudinal evaluation of liver stiffness reveals hepatic cholesterol as the determinant of fibrosis progression in mice

NY Lee, JH Koo - Life Sciences, 2024 - Elsevier
Aims The metabolic dysfunction-associated steatotic liver disease (MASLD) affects
approximately 30% of the global population. While excessive consumption of dietary fat …

A Systematic Review of Statins for the Treatment of Nonalcoholic Steatohepatitis: Safety, Efficacy, and Mechanism of Action

S Zhang, X Ren, B Zhang, T Lan, B Liu - Molecules, 2024 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the liver component of a cluster of conditions,
while its subtype, nonalcoholic steatohepatitis (NASH), emerges as a potentially progressive …

Pine (Pinus koraiensis) Nut Oil Ameliorates Cholesterol Homeostasis and Inflammation via Modulating the miR-34a/122 Pathways in the Liver of Rats Fed a High …

Y Lee, MS Lee, J Lee, IH Kim, Y Kim - The Journal of Nutrition, 2025 - Elsevier
Abstract Background Pine (Pinus koraiensis) nut oil (PNO) has been reported to have
various beneficial effects on hepatic triglyceride accumulation and atherosclerosis in animal …

Evaluation of hepatoprotective and nephroprotective activities of Castanopsis costata extract in rats

MY Alkandahri, A Sadino, E Abriyani… - Biomedical …, 2024 - spandidos-publications.com
The liver and kidneys are important organs for body homeostasis but susceptible to damage
or injury caused by different factors. A number of medicinal plants, such as Castanopsis …