Hydrogel formulations for orthotopic treatment of myocardial infarction

Q Luo, Z Li, B Liu, J Ding - Expert Opinion on Drug Delivery, 2024 - Taylor & Francis
Introduction Myocardial infarction (MI) causes extensive structural and functional damage to
the cardiac tissue due to the significant loss of cardiomyocytes. Early reperfusion is the …

Biomaterials based cardiac patches for the treatment of myocardial infarction

T Chang, C Liu, K Lu, Y Wu, M Xu, Q Yu, Z Shen… - Journal of Materials …, 2021 - Elsevier
Myocardial infarction (MI) is one of the common cardiovascular diseases that occurs with a
blockage in one or more of the coronary arteries to lead to the damage of the myocardium …

Myocardial‐infarction‐responsive smart hydrogels targeting matrix metalloproteinase for on‐demand growth factor delivery

C Fan, J Shi, Y Zhuang, L Zhang, L Huang… - Advanced …, 2019 - Wiley Online Library
Although in situ restoration of blood supply to the infarction region and attenuating pre‐
existing extracellular matrix degradation remain potential therapeutic approaches for …

Biologics and their delivery systems: Trends in myocardial infarction

MA Borrelli, HR Turnquist, SR Little - Advanced drug delivery reviews, 2021 - Elsevier
Cardiovascular disease is the leading cause of death around the world, in which myocardial
infarction (MI) is a precipitating event. However, current therapies do not adequately address …

Toward regeneration of the heart: bioengineering strategies for immunomodulation

A Ferrini, MM Stevens, S Sattler… - Frontiers in …, 2019 - frontiersin.org
Myocardial Infarction (MI) is the most common cardiovascular disease. An average-sized MI
causes the loss of up to 1 billion cardiomyocytes and the adult heart lacks the capacity to …

Sustained release systems for delivery of therapeutic peptide/protein

T Nie, W Wang, X Liu, Y Wang, K Li, X Song… - …, 2021 - ACS Publications
Peptide/protein therapeutics have been significantly applied in the clinical treatment of
various diseases such as cancer, diabetes, etc. owing to their high biocompatibility …

Spatiotemporal delivery of basic fibroblast growth factor to directly and simultaneously attenuate cardiac fibrosis and promote cardiac tissue vascularization following …

Z Fan, Z Xu, H Niu, Y Sui, H Li, J Ma, J Guan - Journal of Controlled …, 2019 - Elsevier
Following myocardial infarction (MI), the destruction of vasculature in the infarcted heart
muscle and progression of cardiac fibrosis lead to cardiac function deterioration …

Recent approaches for angiogenesis in search of successful tissue engineering and regeneration

LVK Reddy, D Murugan, M Mullick… - Current Stem Cell …, 2020 - ingentaconnect.com
Angiogenesis plays a central role in human physiology from reproduction and fetal
development to wound healing and tissue repair/regeneration. Clinically relevant therapies …

Essential role of nonessential amino acid glutamine in atherosclerotic cardiovascular disease

J Chen, S Zhang, J Wu, S Wu, G Xu, D Wei - DNA and Cell Biology, 2020 - liebertpub.com
Atherosclerosis is a major disease that seriously harms human health and is known as the
“number one killer” in developed countries and the leading cause of death worldwide …

[HTML][HTML] Regenerative strategies for the consequences of myocardial infarction: Chronological indication and upcoming visions

M Tajabadi, HG Orimi, MR Ramzgouyan… - Biomedicine & …, 2022 - Elsevier
Heart muscle injury and an elevated troponin level signify myocardial infarction (MI), which
may result in defective and uncoordinated segments, reduced cardiac output, and ultimately …