Abstract Purpose of Review Our goal is to examine the processes—both central and
peripheral—that underlie the development of peripherally-induced neuropathic pain (pNP) …

The past few decades have witnessed a huge leap forward in our understanding of the
mechanistic underpinnings of pain, in normal states where it helps protect from injury, and …

Importance Effective treatments for chronic spinal pain are essential to reduce the related
high personal and socioeconomic costs. Objective To compare pain neuroscience …

Background: Low back pain (LBP) is a heterogeneous disorder including patients with
dominant nociceptive (eg, myofascial low back pain), neuropathic (eg, lumbar …

Background and objective Central sensitization (CS) is a phenomenon associated with
several medical diagnoses, including postcancer pain, low back pain, osteoarthritis …

Trigeminal neuralgia (TN) is a complex orofacial pain syndrome characterized by the
paroxysmal onset of pain attacks in the trigeminal distribution. The underlying mechanism …

Objective To assess the effect of a pain neurophysiology education (PNE) program plus
therapeutic exercise (TE) for patients with chronic low back pain (CLBP). Design Single …

Objectives The aim of this study was to create and validate severity levels for the central
sensitization inventory (CSI), a valid and reliable patient‐reported outcome instrument …

Background: The awareness is growing that central sensitization is of prime importance for
the assessment and management of chronic pain, but its classification is challenging …

Objective Central sensitization (CS), a mechanism explaining the persistence of symptoms,
has been the focus of many research projects. Explanations given to patients with chronic …