A review on dengue vaccine development

SQ Deng, X Yang, Y Wei, JT Chen, XJ Wang, HJ Peng - Vaccines, 2020 - mdpi.com
Dengue virus (DENV) has become a global health threat with about half of the world's
population at risk of infection. Although the disease caused by DENV is self-limiting in the …

Bioinspired yeast-based β-glucan system for oral drug delivery

Y Wu, P Li, Z Jiang, X Sun, H He, P Yan, Y Xu… - Carbohydrate …, 2023 - Elsevier
Oral drug delivery is the preferred route of drug administration for patients, especially those
who need long-term medication. Recently, bioinspired drug delivery systems have emerged …

Dengue vaccine: an update

CH Huang, YT Tsai, SF Wang, WH Wang… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction: Dengue virus is a global health threat, with approximately 390 million dengue
infections annually. Efficient vaccines for dengue prevention are currently lacking. This …

[HTML][HTML] Targets and strategies for vaccine development against dengue viruses

WH Wang, AN Urbina, CY Lin, ZS Yang… - Biomedicine & …, 2021 - Elsevier
Dengue virus (DENV) is a global health threat causing about half of the worldwide
population to be at risk of infection, especially the people living in tropical and subtropical …

Yeast oral vaccines against infectious diseases

N Austriaco - Frontiers in Microbiology, 2023 - frontiersin.org
Vaccines that are delivered orally have several advantages over their counterparts that are
administered via injection. Despite the advantages of oral delivery, however, approved oral …

[HTML][HTML] Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses …

J Pitcovski, N Gruzdev, A Abzach, C Katz, R Ben-Adiva… - Vaccine, 2022 - Elsevier
The rapid spread of the COVID-19 pandemic, with its devastating medical and economic
impacts, triggered an unprecedented race toward development of effective vaccines. The …

Improving expression and assembly of difficult-to-express heterologous proteins in Saccharomyces cerevisiae by culturing at a sub-physiological temperature

KK So, NMT Le, NL Nguyen, DH Kim - Microbial cell factories, 2023 - Springer
Background Escherichia coli heat labile toxin B subunit (LTB) is one of the most popular oral
vaccine adjuvants and intestine adsorption enhancers. It is often expressed as a fusion …

Yeasts as a promising delivery platform for DNA and RNA vaccines

AJD Silva, LS de Macêdo, LRS Leal… - FEMS yeast …, 2021 - academic.oup.com
Yeasts are considered a useful system for the development of vaccines for human and
veterinary health. Species such as Saccharomyces cerevisiae and Pichia pastoris have …

RNA vaccines: yeast as a novel antigen vehicle

AJD Silva, MMG de Sousa, LS de Macêdo… - Vaccines, 2023 - mdpi.com
In the last decades, technological advances for RNA manipulation enabled and expanded
its application in vaccine development. This approach comprises synthetic single-stranded …

Approaches of dengue control: vaccine strategies and future aspects

R Akter, F Tasneem, S Das, MA Soma… - Frontiers in …, 2024 - frontiersin.org
Dengue, caused by the dengue virus (DENV), affects millions of people worldwide every
year. This virus has two distinct life cycles, one in the human and another in the mosquito …